CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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CP0350000
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CHEMICAL NAME :
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Bacitracin A
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CAS REGISTRY NUMBER :
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22601-59-8
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LAST UPDATED :
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199512
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C66-H103-N17-O16-S
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MOLECULAR WEIGHT :
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1422.92
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WISWESSER LINE NOTATION :
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T5N CS AUTJ BYZY2 EVMY1Y&&VMY2VQVMYY2&&VM-WT-23-VM DVM GVM JVM MVM QVMTJ C3Z FY2 I1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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158 mg/kg
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TOXIC EFFECTS :
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Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity)
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REFERENCE :
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BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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474 mg/kg/3D-I
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TOXIC EFFECTS :
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Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
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REFERENCE :
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BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951
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