2885-39-4

• 常用中文名：2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
• 常用英文名：2,6-Piperidinedione,4-[(2R)-2-[(1S,3S,5R)-5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
• CAS号：2885-39-4
• 分子式：C₁₇H₂₅NO₆
• 分子量：339.38400
• 发布时间：2017-06-15 21:35:20
• 更新时间：2024-01-09 20:26:55

名称

• 英文名: 2,6-Piperidinedione, 4-[2-[5-(acetyloxy)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-, [1S-[1.α.(S*),3.β.,5.β.]]
• 英文别名: AXM; Antibiotic from streptomyces albulus; Streptovitacin E 73; Cycloheximide,4-acetoxy-(E-B); Acetyloxycycloheximide; Antibiotic SF-2441; Acetoxycycloheximide; Cycloheximide,acetoxy

物化性质

• 密度: 1.24g/cm3
• 沸点: 529.4ºC at 760mmHg
• 分子式: C₁₇H₂₅NO₆
• 分子量: 339.38400
• 闪点: 274ºC
• 精确质量: 339.16800
• PSA: 109.77000
• LogP: 1.05600
• 储存条件: 库房通风低温干燥,与氧化剂、食品添加剂、酸类分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MA5075000 CHEMICAL NAME : Glutarimide, 3-(2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexy l)ethyl)-, 5-acetate CAS REGISTRY NUMBER : 2885-39-4 LAST UPDATED : 199009 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C17-H25-N-O6 MOLECULAR WEIGHT : 339.43 WISWESSER LINE NOTATION : T6VMVTJ EYQ1- BL6VTJ DOV1 D1 F1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 158 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 170 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 190 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 19 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 920 ug/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 1 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,205,1965

合成路线

131057-04-0 ~67% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

60739-53-9 ~% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

17429-02-6 ~% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

13482-22-9 ~% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

523-86-4 ~% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

131077-81-1 ~% 2885-39-4

文献：Kondo; Oritani; Yamashita Agricultural and biological chemistry, 1990 , vol. 54, # 6 p. 1531 - 1536

上下游产品

上游产品  6
131057-04-0 60739-53-9 17429-02-6 13482-22-9
523-86-4 131077-81-1
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