203662-66-2

• 常用中文名：2-氰基-7-氮杂螺[3.5]壬烷-7-羧酸叔丁酯
• 常用英文名：tert-butyl 2-cyano-7-azaspiro[3.5]nonane-7-carboxylate
• CAS号：203662-66-2
• 分子式：C₁₄H₂₂N₂O₂
• 分子量：250.33700
• 发布时间：2018-12-28 10:30:46
• 更新时间：2024-01-02 16:30:00

名称

• 中文名: 2-氰基-7-氮杂螺[3.5]壬烷-7-羧酸叔丁酯
• 英文名: tert-butyl 2-cyano-7-azaspiro[3.5]nonane-7-carboxylate
• 英文别名: [7-(tert-butoxycarbonyl)-7-azaspiro[3.5]non-2-yl]carbonitrile; 2-CYANO-7-AZASPIRO[3.5]NONANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER

物化性质

• 分子式: C₁₄H₂₂N₂O₂
• 分子量: 250.33700
• 精确质量: 250.16800
• PSA: 53.33000
• LogP: 2.87518
• 储存条件: 2-8℃，密闭，干燥

安全

• 危害码 (欧洲): Xn
• 海关编码: 2933990090

合成路线

773837-37-9 614729-59-8 ~67% 203662-66-2

文献：Pfizer Inc. Patent: US2010/113465 A1, 2010 ; Location in patent: Page/Page column 24 ; US 20100113465 A1

38622-91-2 203661-69-2 ~32% 203662-66-2

文献：Kaneko, Toshihiko; Clark, Richard S. J.; Ohi, Norihito; Ozaki, Fumihiro; Kawahara, Tetsuya; Kamada, Atsushi; Okano, Kazuo; Yokohama, Hiromitsu; Ohkuro, Masayoshi; Muramoto, Kenzo; Takenaka, Osamu; Kobayashi, Seiichi Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 6 p. 675 - 687

203661-69-2 ~% 203662-66-2

文献：Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758

159635-49-1 ~% 203662-66-2

文献：Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758

396653-31-9 ~% 203662-66-2

文献：Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758

240401-28-9 ~% 203662-66-2

文献：Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758

上下游产品

上游产品  6
773837-37-9 614729-59-8 38622-91-2 203661-69-2
159635-49-1 240401-28-9
下游产品  2
873924-12-0 1160247-15-3

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%