204254-96-6

• 常用中文名：5-(戊烷-3-基氧基)-7-氧杂双环[4.1.0]庚-3-烯-3-羧酸乙酯
• 常用英文名：(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate
• CAS号：204254-96-6
• 分子式：C₁₄H₂₂O₄
• 分子量：254.322
• 发布时间：2019-01-07 12:24:42
• 更新时间：2026-07-17 19:55:31

名称

• 中文名: 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯
• 英文名: (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate
• 中文别名: 奥司他韦中间体1; (3R,4R,5S)-4,5-环氧基-3-(1-乙基丙氧基)-1-环己烯-1-甲酸乙酯(环氧化物); 5-(戊烷-3-基氧基)-7-氧杂双环[4.1.0]庚-3-烯-3-羧酸乙酯(环氧物); 5-叠氮奥司他韦; 5-(戊烷-3-基氧基)-7-氧代-双环; 奥司他韦中间体8; 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯 (O6); (3R,4S,5S)-4,5-环氧-3-(1-乙基丙氧基)环己-1-烯-1-羧酸乙酯; 奥司他韦N-5; 奥司他韦环氧中间体; 达菲环氧物; 磷酸奥司他韦环氧物; 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯奥司他韦环氧化物; 奥司他韦杂质ABCDEFGHIJK; 奥司他韦AS1杂质; 5-(戊烷-3-基氧基)-7-氧代-双环4.1.0庚-3-烯-3-羧酸乙酯; 磷酸奥司他; 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯 (磷酸奥斯他韦环氧物); 磷酸奥斯他韦环氧物; 磷酸奥司他韦环氧中间体; 奥司他韦杂质; (1S,5R,6S)-5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯; 奥司他韦中间体-05; 5-(戊烷-3-基氧基)-7-氧代-双环庚-3-烯-3-羧酸乙酯; 奥司他韦中间体-06; 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯/奥司他韦中间体; 奥司他韦 OSA; 奥司他韦杂质加合物; 奥司他韦环氧化物; 奥司他韦中间体(环氧化物); 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯; 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-酸乙酯; 奥司他韦环氧物; 奥司他韦中间体; 磷酸奥司他韦
• 英文别名: 7-Oxabicyclo[4.1.0]ht-3-ene-3-cboxylic acid, 5-(1-ethylpropoxy)-, ethyl ester, (1S,5R,6S); (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]h; Oseltamivir Intermediate 8; Oseltamivir ImpurityABCDEFHIJ; ethyl(3R,4R,5S)-4,5-epoxy-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid; Oseltamivir intermediate; T36 BO EUTJ DOY2&2 FVO2 &&(1S,5R,6S)- Form; [1s-(1a,5b,6a)]-5-(1-ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester; Oseltamivir intermediate 1; Ethyl (3R, 4S, 5S)- 4,5-oxy-3-(1-ethyl-propoxy) cyclohex-1-ene-1- cboxylate oxide); (3R,4R,5S)-4-N-Acetyl(1,1; Ethyl(3R,4S,5S)-4,5 oxy-3-(ethylpropyl)-cyclohex-1-ene-1-Cboxylate; EEC epoxide; (1S 5R 6S)-5-(1-ETHYL PROPOXY)-7-OXABICY CLO[4.1.0]HT-3-ENE-3-CBOXYLIC ACID E THYLESTER( BE NO:7678253 &DATE:16.05.20); (S)-Ethyl-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hta-3,5- diene-3-cboxylate oxide]; 5- (pentane-3-yloxy) -7-oxo-bicyclo [4.1.0] ht-3-ene-3-cboxylic acid ethyl ester / oseltamivir; EEC oxide; Ethyl (1S, 5R,6R)-5-(Pentan-3-yloxyl)-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxyl; Oseltamivir phosphate Intermediate; ETHYL(3R,4S,5S)-4,5-EPOXY-3-(1-ETHYL-PROPOXY)-CYCLOHEX-1-ENE-1-CARBOXYLATE(INTERMEDIATE OF OSELTAMIVIR PHOSPHATE ); Oseltamivir oxy intermediate 06; ETHYL(3R,4S,5S)-4,5-OXY-3-(1-ETHYL-PROPOXY)-CYCLOHEX-1-ENE-1-CBOXYLATE(INTERMEDIATE OF OSELTAMIVIR PHOSPHATE ); (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo; ETHYL(3R,4S,5S)-4,5-OXY-3-(1-ETHYL-PROPOXY)-CYCLOHEX-1-ENE-1-CBOXYLATE; 5- (pentane-3-methoxy) -7-oxabicyclo [4.1.0] htan-3-en-3-cboxylate ethyl ester; (1S,5R,6S)-ETHYL 5-(PENTAN-3-YL-OXY)-7-OXA-BICYCLO[4.1.0]HT-3-ENE-3-CBOXYLATE; (1S,5R,6S)-5-(1-Ethyl-propoxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester; MFCD08063944; Oxabicyclo[4.1.0]ht-3-ene-3-cboxylicacid,5-(1-ethylpropoxy)-,ethylester,(1S,5R,6S); ETHYL(3R,4S,5S)-4,5-EPOXY-3-(1-ETHYL-PROPOXY)-CYCLOHEX-1-ENE-1-CARBOXYLATE; (1S,5R,6S)Ethyl 5-(pentan-3-yloxy)-7-oxa-bicyclo[4.1.0]ht-3-en-3-cboxylate; 7-Oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid,5-(1-ethylpropoxy)-,ethyl ester,(1S,5R,6S); (1S,5R,6R)-5-pentan-3-yloxy-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxylic acid ethyl ester; (1S,5R,6S); (1S,5R,6S)-5-(1-Ethyl-propoxy)-7-oxa-bicyclo[4.1.0]ht-3-ene-3-cboxylic acid ethyl ester; (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]ht-3-ene-3-cboxylate (O6); 7-Oxabicyclo[4.1.0]ht-3-ene-3-cboxylic acid, 5-(1-ethylpropoxy)-, ethyl ester, [1S-(1α,5β,6α)]; [1s-(1a,5b,6a)]-5-(1-ethylpropoxy)-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxylic acid ethyl ester; 5-(pentane - 3-oxyl) -7-oxyl - dicyclic[4.1.0] ht-3-ene-3-cboxylate, ethyl ester; 7-Oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid, 5-(1-ethylpropoxy)-, ethyl ester; ethyl(3R, 4R, 5S)-4,5-oxy-3-(1-ethylpropoxy)-1-cyclohexene-1-cboxylic acid; (1S,5R,6S)-ethyl 5-(pentan-3-yloxy); Ethyl 5-(3-pentanyloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate; Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate; Oseltamivir oxide; Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]ht-3-ene-3-cboxylate; Ethyl (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate; ethyl (1S,5R,6S)-5-(1-ethylpropoxy)-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxylate; Ethyl (1S,5R,6S)-5-(3-pentanyloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate; Oseltamivir Impurity463; ethyl (1S,5R,6S)-5-(1-ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate; Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate; (1S,5R,6S)-Ethyl 5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxylate; Oseltamivir intermediates; Ethyl5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]ht-3-ene-3-cboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 336.5±42.0 °C at 760 mmHg
• 熔点: 56-57ºC
• 分子式: C₁₄H₂₂O₄
• 分子量: 254.322
• 闪点: 145.1±27.9 °C
• 精确质量: 254.151810
• PSA: 48.06000
• LogP: 3.47
• 外观性状: 白色至灰白色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.492
• 储存条件: -20°C Freezer

合成路线

204254-92-2 ~% 204254-96-6

文献：WO2007/74091 A2, ; Page/Page column 18; 23 ;

204254-90-0 ~% 204254-96-6

文献：Journal of Organic Chemistry, , vol. 63, # 13 p. 4545 - 4547

204254-84-2 ~% 204254-96-6

文献：Journal of Organic Chemistry, , vol. 63, # 13 p. 4545 - 4547

204254-81-9 ~% 204254-96-6

文献：US2014/51756 A1, ;

77-95-2 ~% 204254-96-6

文献：US2014/51756 A1, ;

77-76-9 ~% 204254-96-6

文献：US2014/51756 A1, ;

32384-42-2 ~% 204254-96-6

文献：US2014/51756 A1, ;

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