Oct3/4-inducer-1

• 常用名: Oct3/4-inducer-1
• 英文名: Oct3/4-inducer-1
• CAS号: 1016535-83-3
• 分子量: 241.260
• 密度: 1.2±0.1 g/cm3
• 沸点: 391.7±27.0 °C at 760 mmHg
• 分子式: C₁₅H₁₂FNO
• 熔点: N/A
• 闪点: 190.7±23.7 °C

Oct3/4-inducer-1用途

Oct3/4-inducer-1 (compound 2) 是一种有效的 Oct3/4 诱导剂。Oct3/4-inducer-1 促进 Oct3/4 的表达和稳定,增强其在多种人体细胞中的转录活性。

Oct3/4-inducer-1名称

• 英文名: {4-[(4-Fluorobenzyl)oxy]phenyl}acetonitrile

Oct3/4-inducer-1生物活性

• 描述: Oct3/4-inducer-1 (compound 2) 是一种有效的 Oct3/4 诱导剂。Oct3/4-inducer-1 促进 Oct3/4 的表达和稳定,增强其在多种人体细胞中的转录活性。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> OCT3/4
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015;58(12):4976-4983.

Oct3/4-inducer-1物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 391.7±27.0 °C at 760 mmHg
• 分子式: C₁₅H₁₂FNO
• 分子量: 241.260
• 闪点: 190.7±23.7 °C
• 精确质量: 241.090286
• LogP: 3.07
• InChIKey: PXFUNIXWNXRVEJ-UHFFFAOYSA-N
• SMILES: N#CCc1ccc(OCc2ccc(F)cc2)cc1
• 外观性状: 浅黄色固体
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.568
• 储存条件: -20℃

Oct3/4-inducer-1靶点实验

查看更多实验

实验名称：Activation of human Oct3/4 in NCCIT cells transfected with firefly luciferase gene as... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3583941

实验名称：Induction of cell cycle arrest in human adult primary fibroblasts assessed as accumul... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584606

实验名称：Induction of cell cycle arrest in human adult primary fibroblasts assessed as accumul... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584607

实验名称：Activation of human Oct3/4 in human adult primary fibroblasts at 20 uM by immunoblott... 来源：ChEMBL 靶标：POU domain, class 5, transcription factor 1 External Id：CHEMBL3584492

实验名称：Induction of human Oct3/4 gene expression in human adult primary fibroblasts assessed... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584493

实验名称：Induction of human Sox2 protein expression in human adult primary fibroblasts assesse... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584490

实验名称：Induction of human Nanog protein expression in human adult primary fibroblasts assess... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584491

实验名称：Induction of human Rex1 gene expression in human adult primary fibroblasts assessed a... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584496

实验名称：Induction of human c-Myc gene expression in human adult primary fibroblasts assessed ... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584497

实验名称：Induction of human Nanog gene expression in human adult primary fibroblasts assessed ... 来源：ChEMBL 靶标：Fibroblast External Id：CHEMBL3584494

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Oct3/4-inducer-1英文别名

• MFCD09929139
• {4-[(4-Fluorobenzyl)oxy]phenyl}acetonitrile
• 2-(4-(4-Methoxybenzyloxy)phenyl)acetonitrile