α,β-亚甲基腺苷 5'-二磷酸钠盐

更新时间：2024-01-16 14:01:08

α,β-亚甲基腺苷 5'-二磷酸钠盐结构式	常用名	α,β-亚甲基腺苷 5'-二磷酸钠盐	英文名	ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
	CAS号	104835-70-3	分子量	469.19200
	密度	N/A	沸点	N/A
	分子式	C₁₁H₁₅N₅Na₂O₉P₂	熔点	N/A
	MSDS	美版	闪点	N/A

用途

αβ-亚甲基腺苷5′-二磷酸（AMP-CP）是ADP类似物，具有抑制胞外核苷酸酶/CD73 的能力，通过CD73/胞外-5′-核苷酸酶，用于研究腺苷能信号调控。

中文名	Α,Β-亚甲基腺苷 5'-二磷酸钠盐
英文名	α,β-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
英文别名	更多

分子式	C₁₁H₁₅N₅Na₂O₉P₂
分子量	469.19200
精确质量	469.01400
PSA	248.65000
外观性状	固体
储存条件	20°C

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	26-36
危险品运输编码	NONH for all modes of transport

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

Eur. J. Immunol. 38 , 2718-2726, (2008)

IFN-beta treatment reduces the relapse rate in MS but its mechanism of action remains incompletely understood. Our aim was to clarify the beneficial effect of IFN-beta in the treatment of MS. We asses...

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.

Eur. J. Immunol. 41 , 1231-1241, (2011)

CD73/ecto-5'-nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The contribution of host CD73 to tumor growth and anti...

Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.

Pharmacology 84 , 196-202, (2009)

Extracellular ATP may be metabolized to AMP and adenosine by the ectonucleotidases CD39 and CD73 and, in this study, we characterized the pathways for adenosine formation in human urinary tract epithe...

AMP-CP SODIUM SALT

A,B-methyleneadenosine 5'-diphosphate*sodium