Cardiogenol C HCl

• 常用名: Cardiogenol C HCl
• 英文名: Cardiogenol C (hydrochloride)
• CAS号: 1049741-55-0
• 分子量: 296.75300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₇ClN₄O₂
• 熔点: N/A
• 闪点: N/A

Cardiogenol C HCl用途

Cardiogenol C盐酸盐是一种细胞渗透性的嘧啶化合物, 有效诱导胚胎干细胞分化为心肌 (EC50= 100 nM)。

Cardiogenol C HCl名称

• 中文名: 心肌素C盐酸盐
• 英文名: 2-({2-[(4-Methoxyphenyl)amino]-4-pyrimidinyl}amino)ethanol hydroc hloride (1:1)

Cardiogenol C HCl生物活性

• 描述: Cardiogenol C盐酸盐是一种细胞渗透性的嘧啶化合物, 有效诱导胚胎干细胞分化为心肌 (EC50= 100 nM)。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> β-catenin
  信号通路 >> 干细胞及 Wnt 通路 >> Wnt信号
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Jasmin, et al. Chemical induction of cardiac differentiation in p19 embryonal carcinoma stem cells. Stem Cells Dev. 2010 Mar;19(3):403-412.

  [2]. Yau WW, et al. Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. Proteome Sci. 2011 Jan 19;9(1):3.

Cardiogenol C HCl物理化学性质

• 分子式: C₁₃H₁₇ClN₄O₂
• 分子量: 296.75300
• 精确质量: 296.10400
• PSA: 82.53000
• LogP: 1.92990
• 外观性状: 白色至类白色粉末
• 储存条件: -20℃

Cardiogenol C HCl靶点实验

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实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

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Cardiogenol C HCl英文别名

• Combretastatin A4
• Cardiogenol C,Hydrochloride
• Cardiogenol C (hydrochloride)