PPARγ agonist 8

• 常用名: PPARγ agonist 8
• 英文名: PPARγ agonist 8
• CAS号: 1049800-41-0
• 分子量: 380.36
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₂F₄O₂S
• 熔点: N/A
• 闪点: N/A

PPARγ agonist 8用途

PPARγ激动剂8是PPARγ的激动剂。PPARγ激动剂8诱导过氧化物酶体增殖物反应元件(PPRE)-萤光素酶活性,EC50为0.2μM[1]。

PPARγ agonist 8名称

• 英文名: PPARγ agonist 8

PPARγ agonist 8生物活性

• 描述: PPARγ激动剂8是PPARγ的激动剂。PPARγ激动剂8诱导过氧化物酶体增殖物反应元件(PPRE)-萤光素酶活性,EC50为0.2μM[1]。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> PPAR
  研究领域 >> 代谢疾病
• 靶点实验:

  PPARγ

• 参考文献:

  [1]. Felts AS, et.al. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. J Med Chem. 2008 Aug 28;51(16):4911-9.

PPARγ agonist 8物理化学性质

• 分子式: C₁₉H₁₂F₄O₂S
• 分子量: 380.36
• InChIKey: NPPDMRLSURBHGR-KPKJPENVSA-N
• SMILES: O=C(O)CC1=CC(=Cc2ccc(SC(F)(F)F)cc2)c2ccc(F)cc21

PPARγ agonist 8靶点实验

查看更多实验

实验名称：Inhibition of cyclooxygenase 2 upto 4 uM 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL998735

实验名称：Inhibition of cyclooxygenase 1 upto 4 uM 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL998734

实验名称：Inhibition of ovine COX-1 using [14C] arachidonic acid as substrate at 4 uM preincuba... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL2066341

实验名称：Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of ... 来源：ChEMBL 靶标：Peroxisome proliferator-activated receptor gamma External Id：CHEMBL998733

实验名称：Inhibition of mouse COX-2 using [14C] arachidonic acid as substrate at 4 uM preincuba... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL2066342

实验名称：Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of ... 来源：ChEMBL 靶标：Peroxisome proliferator-activated receptor gamma External Id：CHEMBL998732

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

共7条，当前第1页，共1页

1