ACS67

• 常用名: ACS67
• 英文名: ACS67
• CAS号: 1088434-86-9
• 分子量: 598.836
• 密度: 1.3±0.1 g/cm3
• 沸点: 777.4±70.0 °C at 760 mmHg
• 分子式: C₃₂H₃₈O₅S₃
• 熔点: N/A
• 闪点: 424.0±35.7 °C

ACS67用途

ACS67 is an F-series prostaglandin (PG) analog for treatment of glaucoma. ACS 67 reduces intra-ocular pressure (IOP) and increases levels of reduced glutathione and cGMP in the aqueous humor of glaucomatous pigmented rabbits. ACS67 also acts as a neuroprotectant that stimulates GSH levels.

ACS67名称

• 英文名: acs 67

ACS67物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 777.4±70.0 °C at 760 mmHg
• 分子式: C₃₂H₃₈O₅S₃
• 分子量: 598.836
• 闪点: 424.0±35.7 °C
• 精确质量: 598.188110
• PSA: 175.56000
• LogP: 5.48
• InChIKey: JEEWZRQQYWVJCX-WEWVERJPSA-N
• SMILES: O=C(CCCC=CCC1C(O)CC(O)C1CCC(O)CCc1ccccc1)Oc1ccc(-c2cc(=S)ss2)cc1
• 蒸汽压: 0.0±2.8 mmHg at 25°C
• 折射率: 1.668

ACS67靶点实验

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实验名称：Reduction in intraocular pressure in carbomer-induced glaucoma in pigmented rabbit at... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL964118

实验名称：Effect on intraocular pressure in carbomer-induced glaucoma in New Zealand albino rab... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL964119

实验名称：Effect on intraocular pressure in carbomer-induced glaucoma in pigmented rabbit asses... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL964117

实验名称：Effect on intraocular pressure in carbomer-induced glaucoma in pigmented rabbit asses... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL964120

实验名称：Reduction in intraocular pressure in carbomer-induced glaucoma in pigmented rabbit at... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL953521

实验名称：Increase in glutathione levels in aqueous humor of carbomer-induced glaucomatous pigm... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL954369

实验名称：Increase in cGMP levels in aqueous humor of carbomer-induced glaucomatous pigmented r... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL954370

实验名称：Increase in glutathione levels in aqueous humor of normotensive pigmented rabbit at 0... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL954367

实验名称：Increase in glutathione levels in aqueous humor of normotensive pigmented rabbit at 0... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL954368

实验名称：Increase in glutathione levels in aqueous humor of normotensive pigmented rabbit at 0... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL954366

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ACS67英文别名

• 4-(3-Thioxo-3H-1,2-dithiol-5-yl)phenyl (5Z)-7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]-5-heptenoate
• 5-p-nitrobenzylidene-2-thiohydantoin