1,2,5,6-四氢-1-甲基-3-吡啶羧酸 2-丙炔-1-基酯氢溴酸盐

更新时间：2026-07-16 12:25:30

1,2,5,6-四氢-1-甲基-3-吡啶羧酸 2-丙炔-1-基酯氢溴酸盐结构式	常用名	1,2,5,6-四氢-1-甲基-3-吡啶羧酸 2-丙炔-1-基酯氢溴酸盐	英文名	ARECAIDINE PROPARGYL ESTER HYDROBROMIDE (APE)
	CAS号	116511-28-5	分子量	260.12800
	密度	N/A	沸点	252.5ºC at 760mmHg
	分子式	C₁₀H₁₄BrNO₂	熔点	179 °C
	MSDS	中文版美版	闪点	97.2ºC

中文名	槟榔碱炔丙基酯氢溴酸盐
英文名	Arecaidine propargyl ester hydrobromide
英文别名	更多

沸点	252.5ºC at 760mmHg
熔点	179 °C
分子式	C₁₀H₁₄BrNO₂
分子量	260.12800
闪点	97.2ºC
精确质量	259.02100
PSA	29.54000
LogP	1.32070
InChIKey	LRPUAFALRBYLTA-UHFFFAOYSA-N
SMILES	Br.C#CCOC(=O)C1=CCCN(C)C1
外观性状	白色固体
蒸汽压	0.0192mmHg at 25°C
储存条件	2-8℃

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲)	22-24/25
危险品运输编码	NONH for all modes of transport

Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer.

Mol. Cancer Ther. 13(12) , 3123-36, (2014)

Ovarian cancer is the second leading cause of cancer-related death in women worldwide. Despite optimal cytoreduction and adequate adjuvant therapies, initial tumor response is often followed by relaps...

Perilipin-related protein regulates lipid metabolism in C. elegans.

PeerJ 3 , e1213, (2015)

Perilipins are lipid droplet surface proteins that contribute to fat metabolism by controlling the access of lipids to lipolytic enzymes. Perilipins have been identified in organisms as diverse as met...

A Fluorescent Probe to Measure DNA Damage and Repair.

PLoS ONE 10 , e0131330, (2015)

DNA damage and repair is a fundamental process that plays an important role in cancer treatment. Base excision repair (BER) is a major repair pathway that often leads to drug resistance in DNA-targete...

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源：The Scripps Research Institute Molecular Screening Center
靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源：The Scripps Research Institute Molecular Screening Center
靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1266185

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源：Burnham Center for Chemical Genomics
靶标：N/A
External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源：Broad Institute
靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源：Broad Institute
靶标：N/A
External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Dicer-mediated maturation of pre-microRNA
来源：Center for Chemical Genomics, University of Michigan
靶标：N/A
External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源：The Scripps Research Institute Molecular Screening Center
靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id：SIAE_INH_FP_1536_1X%INH PRUN

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