节球毒素

更新时间：2024-01-03 15:40:17

节球毒素结构式	常用名	节球毒素	英文名	Nodularin
	CAS号	118399-22-7	分子量	824.963
	密度	1.3±0.1 g/cm3	沸点	N/A
	分子式	C₄₁H₆₀N₈O₁₀	熔点	N/A
	MSDS	中文版美版	闪点	11℃
	符号	GHS02, GHS06, GHS08	信号词	Danger

中文名	节球毒素
英文名	(2Z,5R,6S,9S,12S,13S,16R)-9-[3-(diaminomethylideneamino)propyl]-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentazacyclononadecane-5,16-dicarboxylic acid
英文别名	更多

密度	1.3±0.1 g/cm3
分子式	C₄₁H₆₀N₈O₁₀
分子量	824.963
闪点	11℃
精确质量	824.443237
PSA	282.44000
LogP	-0.56
折射率	1.598
储存条件	−20°C
水溶解性	methanol: 2 mg/mL Further dilute to 10% (v/v) methanol. Store solutions at −20°C for up to six months.
更多	1. 性状：无可用 2. 密度（g/mL,25/4℃）：无可用 3. 相对蒸汽密度（g/mL,空气=1）：无可用计算化学数据纠错 \| 编辑 1.疏水参数计算参考值（XlogP）:1.7 2.氢键供体数量:8 3.氢键受体数量:11 4.可旋转化学键数量:13 5.互变异构体数量:216 6.拓扑分子极性表面积285 7.重原子数量:59 8.表面电荷:0 9.复杂度:1620 10.同位素原子数量:0 11.确定原子立构中心数量:8 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:3 14.不确定化学键立构中心数量:0 15.共价键单元数量:1

节球毒素MSDS英文版

符号	GHS02, GHS06, GHS08
信号词	Danger
危害声明	H225-H301 + H311 + H331-H370
警示性声明	P210-P260-P280-P301 + P310-P311
个人防护装备	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
危害码 (欧洲)	T: Toxic;
风险声明 (欧洲)	23/24/25-38
安全声明 (欧洲)	36/37-45
危险品运输编码	UN 2811 6.1/PG 2
WGK德国	3
RTECS号	GU2294250

Nod-AM2

1187315-06-5

节球毒素

118399-22-7

文献：Journal of Medicinal Chemistry, , vol. 52, # 18 p. 5759 - 5762

Nod-PM2

1187315-08-7

节球毒素

118399-22-7

文献：Journal of Medicinal Chemistry, , vol. 52, # 18 p. 5759 - 5762

节球毒素上游产品 2
CAS号1187315-06-5 Nod-AM2 CAS号1187315-08-7 Nod-PM2
节球毒素下游产品 0

Biological treatment options for cyanobacteria metabolite removal--a review.

Water Res. 46(5) , 1536-48, (2012)

The treatment of cyanobacterial metabolites can consume many resources for water authorities which can be problematic especially with the recent shift away from chemical- and energy-intensive processe...

Simultaneous detection of nine cyanotoxins in drinking water using dual solid-phase extraction and liquid chromatography-mass spectrometry.

Toxicon 58(2) , 209-18, (2011)

A solid-phase extraction (SPE)-liquid chromatography (LC)-mass spectrometry (MS) method was developed to concentrate and detect nine cyanotoxins simultaneously, including six microcystins (MCs) congen...

Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development.

Anticancer Agents Med. Chem. 11(1) , 4-18, (2011)

Microcystin-LR and nodularin, along with okadaic acid, are potent inhibitors of protein phosphatases 1 and 2A (PP1 and PP2A). The mechanisms of action of microcystin-LR and nodularin in the liver and ...

(2Z,5R,6S,9S,12S,13S,16R)-9-{3-[(diaminomethylidene)amino]propyl}-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentaazacyclononadecane-5,16-dicarboxylic acid

Nodularin

(2Z,5R,6S,9S,12S,13S,16R)-9-(3-Carbamimidamidopropyl)-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentaazacyclononadecane-5,16-dicarboxylic acid

1,4,8,11,15-Pentaazacyclononadecane-5,16-dicarboxylic acid, 9-[3-[(aminoiminomethyl)amino]propyl]-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-, (2Z,5R,6S,9S,12S,13S,16R)-

Nodularin solution

1,4,8,11,15-Pentaazacyclononadecane,cyclic peptide

MFCD00165004

1,4,8,11,15-pentaazacyclononadecane-5,16-dicarboxylic acid, 9-[3-[(diaminomethylene)amino]propyl]-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenyl-1,3-heptadien-1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-, (2Z,5R,6S,9S,12S,13S,16R)-