EMD638683 S-Form

• 常用名: EMD638683 S-Form
• 英文名: EMD638683 (S-Form)
• CAS号: 1184940-46-2
• 分子量: 364.34300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₈F₂N₂O₄
• 熔点: N/A
• 闪点: N/A

EMD638683 S-Form用途

EMD638683 (S-Form)是SGK1抑制剂,IC50> 300 nM。

EMD638683 S-Form名称

• 中文名: EMD638683 S-Form
• 英文名: N'-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide

EMD638683 S-Form生物活性

• 描述: EMD638683 (S-Form)是SGK1抑制剂,IC50> 300 nM。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> SGK
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46.

  [2]. Sgk1 inhibitors for the prophylaxis and/or therapy of viral diseases and/or carcinomas US 20110060050 A1

EMD638683 S-Form物理化学性质

• 分子式: C₁₈H₁₈F₂N₂O₄
• 分子量: 364.34300
• 精确质量: 364.12300
• PSA: 102.15000
• LogP: 3.26700
• InChIKey: SSNAPUUWBPZGOY-INIZCTEOSA-N
• SMILES: CCc1c(C(=O)NNC(=O)C(O)c2cc(F)cc(F)c2)ccc(O)c1C
• 储存条件: 2-8℃

EMD638683 S-Form靶点实验

查看更多实验

实验名称：Diffuse intrinsic pontine glioma (SU-DIPG-XVII) cell line screen of MIPE5.0 library: ... 来源：15316 靶标：N/A External Id：s-dipg-DIPG17_CTG48h_mipe5_0-1

实验名称：qHTS drug screen for cell cycle checkpoint inhibitors in PARPi-resistant BRCA-mutant ... 来源：NCGC External Id：FGL-PARP_PEO-CTG96h-MIPE5.0-p1

实验名称：Diffuse intrinsic pontine glioma (SU-DIPG-XXV) cell line screen of MIPE5.0 library: v... 来源：15316 靶标：N/A External Id：s-dipg-DIPG25-MIPE5.0-CTF48h-p1

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-SW13-72hr

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-H295R-72hr

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Diffuse intrinsic pontine glioma (SU-DIPG-XIII) cell line screen of MIPE5.0 library: ... 来源：15316 靶标：N/A External Id：s-dipg-DIPG13_CTG48h_mipe5_0-1

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Diffuse intrinsic pontine glioma (SU-DIPG-XXV) cell line screen of MIPE5.0 library: v... 来源：15316 靶标：N/A External Id：s-dipg-DIPG25_CTG48h_mipe5_0-2

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EMD638683 S-Form英文别名

• cs-0660
• EMD638683 (S-Form)