莫吉司坦

• 常用名: 莫吉司坦
• 英文名: Moguisteine
• CAS号: 119637-67-1
• 分子量: 339.407
• 密度: 1.2±0.1 g/cm3
• 沸点: 506.8±50.0 °C at 760 mmHg
• 分子式: C₁₆H₂₁NO₅S
• 熔点: 72-76ºC
• 闪点: 260.3±30.1 °C

莫吉司坦用途

Moguisteine(BBR-2173)是新型外周非麻醉性止咳化合物。

莫吉司坦名称

• 中文名: 莫吉司坦
• 英文名: Moguisteine
• 中文别名: (+/-)-2-(2-甲氧基苯氧基)-甲基-3-乙氧基羰基乙酰基-1,3-噻唑啉

莫吉司坦生物活性

• 描述: Moguisteine(BBR-2173)是新型外周非麻醉性止咳化合物。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Gallico, L., et al., Moguisteine: a novel peripheral non-narcotic antitussive drug. Br J Pharmacol, 1994. 112(3): p. 795-800.

  [2]. Gallico, L., et al., Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. Eur Respir J, 1996. 9(3): p. 478-85.

莫吉司坦物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 506.8±50.0 °C at 760 mmHg
• 熔点: 72-76ºC
• 分子式: C₁₆H₂₁NO₅S
• 分子量: 339.407
• 闪点: 260.3±30.1 °C
• 精确质量: 339.114044
• PSA: 90.37000
• LogP: 2.18
• InChIKey: WSYVIAQNTFPTBI-UHFFFAOYSA-N
• SMILES: CCOC(=O)CC(=O)N1CCSC1COc1ccccc1OC
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.549
• 储存条件: Refrigerator

莫吉司坦MSDS

莫吉司坦MSDS英文版

莫吉司坦毒性和生态

莫吉司坦安全信息

• 危害码 (欧洲): Xi

莫吉司坦靶点实验

查看更多实验

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：ULK1_INH_LUMI_1536_1X%INH PRUN

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Primary high throughput screening by co-culture imaging for identification hits as a ... 来源：23209 靶标：N/A External Id：UIHTS20180925

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Inhibition of cell viability relative to arbidol control (inhibition index > 1 indica... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303819

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay 来源：24386 靶标：N/A External Id：Sarm1 Tir NADase inhibitors screen

实验名称：Acute toxicity was determined in mice upon peroral administration 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL720720

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莫吉司坦英文别名

• Ethyl (±)-2-((o-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropionate
• Ethyl 3-{2-[(2-methoxyphenoxy)methyl]-1,3-thiazolidin-3-yl}-3-oxopropanoate
• 3-Thiazolidinepropanoic acid, 2-[(2-methoxyphenoxy)methyl]-β-oxo-, ethyl ester
• (±)-2-((2-Methoxyphenoxy)methyl)-b-oxo-3-thiazolidinepropanoic Acid Ethyl Ester
• UNII:6Y556547YY