(8Z,11Z,14Z,17Z)-ICOSA-8,11,14,17-四烯酸乙酯

• 常用名: (8Z,11Z,14Z,17Z)-ICOSA-8,11,14,17-四烯酸乙酯
• 英文名: ω-3 Arachidonic Acid ethyl ester
• CAS号: 123940-93-2
• 分子量: 332.520
• 密度: 0.9±0.1 g/cm3
• 沸点: 418.1±24.0 °C at 760 mmHg
• 分子式: C₂₂H₃₆O₂
• 熔点: N/A
• 闪点: 100.7±21.2 °C

用途

ω-3花生四烯酸乙酯是一种罕见的多不饱和脂肪酸,在膳食中含量很低。众所周知,Omega-3脂肪酸对婴儿的生长发育至关重要,它们可以预防心脏病、血栓、高血压、炎症和自身免疫性疾病。在人类血小板膜中,ω-3花生四烯酸以14μM的Ki抑制花生四烯酸辅酶a合成酶。它还抑制小牛脑提取物中的花生四烯酸辅酶A合成酶,IC50约为5μM。Omega-3乙基花生四烯酸是更亲脂性的游离酸。

名称

• 中文名: (8Z,11Z,14Z,17Z)-ICOSA-8,11,14,17-四烯酸乙酯
• 英文名: ethyl (8Z,11Z,14Z,17Z)-icosatetraenoate

生物活性

• 描述: ω-3花生四烯酸乙酯是一种罕见的多不饱和脂肪酸,在膳食中含量很低。众所周知,Omega-3脂肪酸对婴儿的生长发育至关重要,它们可以预防心脏病、血栓、高血压、炎症和自身免疫性疾病。在人类血小板膜中,ω-3花生四烯酸以14μM的Ki抑制花生四烯酸辅酶a合成酶。它还抑制小牛脑提取物中的花生四烯酸辅酶A合成酶,IC50约为5μM。Omega-3乙基花生四烯酸是更亲脂性的游离酸。
• 相关类别:
  研究领域 >> 其他

物理化学性质

• 密度: 0.9±0.1 g/cm3
• 沸点: 418.1±24.0 °C at 760 mmHg
• 分子式: C₂₂H₃₆O₂
• 分子量: 332.520
• 闪点: 100.7±21.2 °C
• 精确质量: 332.271515
• PSA: 26.30000
• LogP: 7.88
• InChIKey: LKBDTOYINRNCSY-AFSLFLIVSA-N
• SMILES: CCC=CCC=CCC=CCC=CCCCCCCC(=O)OCC
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.485

毒性和生态

靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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英文别名

• Ethyl (8Z,11Z,14Z,17Z)-8,11,14,17-icosatetraenoate
• .ω.-3 Arachidonic Acid ethyl ester