NIOCH 14

• 常用名: NIOCH 14
• 英文名: NIOCH 14
• CAS号: 1268015-38-8
• 分子量: 394.34
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₇F₃N₂O₄
• 熔点: N/A
• 闪点: N/A

NIOCH 14用途

NIOCH 14是一种抗病毒药物和前药。NIOCH 14对正痘病毒具有抗病毒活性。NIOCH 14可以显著降低感染小鼠的比例和肺部的病毒生成水平。NIOCH 14可用于研究抗天花[1][2]。

NIOCH 14名称

• 英文名: NIOCH 14

NIOCH 14生物活性

• 描述: NIOCH 14是一种抗病毒药物和前药。NIOCH 14对正痘病毒具有抗病毒活性。NIOCH 14可以显著降低感染小鼠的比例和肺部的病毒生成水平。NIOCH 14可用于研究抗天花[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 靶点实验:

  Orthopoxviruses[1]

• 参考文献:

  [1]. Sokolova AS, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021;354(6):e2100038.

  [2]. Mazurkov OY, et al. New effective chemically synthesized anti-smallpox compound NIOCH-14. J Gen Virol. 2016;97(5):1229-1239.

NIOCH 14物理化学性质

• 分子式: C₁₉H₁₇F₃N₂O₄
• 分子量: 394.34

NIOCH 14靶点实验

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实验名称：Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Cowp... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225282

实验名称：Antiviral activity against Cowpox virus Grishak infected in Vero cells measured after... 来源：ChEMBL 靶标：Cowpox virus External Id：CHEMBL5225281

实验名称：Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for ectr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225284

实验名称：Antiviral activity against Vaccinia virus infected in Vero cells measured after 4 day... 来源：ChEMBL 靶标：Vaccinia virus External Id：CHEMBL5349955

实验名称：Antiviral activity against ectromelia virus K-1 infected in Vero cells measured after... 来源：ChEMBL 靶标：Ectromelia virus External Id：CHEMBL5225283

实验名称：Cytotoxicity against African green monkey Vero cells measured after 4 days by colorim... 来源：ChEMBL 靶标：Vero External Id：CHEMBL5225278

实验名称：Antiviral activity against ectromelia virus K-1 infected in Vero cells measured after... 来源：ChEMBL 靶标：Ectromelia virus External Id：CHEMBL5349953

实验名称：Antiviral activity against Monkeypox virus V79-1-005 infected in Vero cells measured ... 来源：ChEMBL 靶标：Monkeypox virus External Id：CHEMBL5349954

实验名称：Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Vacc... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225280

实验名称：Antiviral activity against Vaccinia virus Copenhagen infected in Vero cells measured ... 来源：ChEMBL 靶标：Vaccinia virus External Id：CHEMBL5225279

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