5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺

• 常用名: 5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺
• 英文名: Taminadenant
• CAS号: 1337962-47-6
• 分子量: 306.121
• 密度: 1.9±0.1 g/cm3
• 沸点: 574.9±60.0 °C at 760 mmHg
• 分子式: C₁₀H₈BrN₇
• 熔点: N/A
• 闪点: 301.5±32.9 °C

5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺用途

Taminadenant 是腺苷受体 (adenosine receptor) 的拮抗剂。

5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺名称

• 中文名: 5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺
• 英文名: 5-Bromo-2,6-di(1H-pyrazol-1-yl)-4-pyrimidinamine

5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺生物活性

• 描述: Taminadenant 是腺苷受体 (adenosine receptor) 的拮抗剂。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 腺苷受体
• 靶点实验:

  Adenosine receptor[1]

• 参考文献:

  [1]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, 2018, 32(4).

5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺物理化学性质

• 密度: 1.9±0.1 g/cm3
• 沸点: 574.9±60.0 °C at 760 mmHg
• 分子式: C₁₀H₈BrN₇
• 分子量: 306.121
• 闪点: 301.5±32.9 °C
• 精确质量: 305.002441
• LogP: -0.47
• InChIKey: ATFXVNUWQOXRRU-UHFFFAOYSA-N
• SMILES: Nc1nc(-n2cccn2)nc(-n2cccn2)c1Br
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.851
• 储存条件: 2-8℃

5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺靶点实验

查看更多实验

实验名称：Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807229

实验名称：Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807326

实验名称：Ratio of FC for induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807363

实验名称：Induction of INF-gamma production in anti-CD3/CD28-stimulated human PBMCs assessed as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807235

实验名称：Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807362

实验名称：Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807234

实验名称：cAMP Production Assay from US Patent US8796284: "4-aminopyrimidine derivatives and th... 来源：BindingDB 靶标：N/A External Id：BindingDB_6428_2

实验名称：Competition Radioligand Binding Assay from US Patent US8796284: "4-aminopyrimidine de... 来源：BindingDB 靶标：N/A External Id：BindingDB_6428_1

实验名称：Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807318

实验名称：Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4807375

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5-溴-2,6-二(1H-吡唑-1-基)嘧啶-4-胺英文别名

• 5-Bromo-2,6-di(1H-pyrazol-1-yl)-4-pyrimidinamine