9-羟基铁屎米酮

• 常用名: 9-羟基铁屎米酮
• 英文名: 9-hydroxycanthin-6-one
• CAS号: 138544-91-9
• 分子量: 236.23
• 密度: 1.5±0.1 g/cm3
• 沸点: 410.1±45.0 °C at 760 mmHg
• 分子式: C₁₄H₈N₂O₂
• 熔点: N/A
• 闪点: 201.8±28.7 °C

9-羟基铁屎米酮用途

9-羟基斑蝥素-6-酮是一种生物碱化合物。9,10-二甲氧基斑蝥素-6-酮具有NF-κB抑制作用,IC50为3.8μM[1]。

9-羟基铁屎米酮名称

• 中文名: 9-羟基铁屎米酮
• 英文名: 9-hydroxycanthin-6-one

9-羟基铁屎米酮生物活性

• 描述: 9-羟基斑蝥素-6-酮是一种生物碱化合物。9,10-二甲氧基斑蝥素-6-酮具有NF-κB抑制作用,IC50为3.8μM[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Thi Van Anh Tran, et al. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8.

9-羟基铁屎米酮物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 410.1±45.0 °C at 760 mmHg
• 分子式: C₁₄H₈N₂O₂
• 分子量: 236.23
• 闪点: 201.8±28.7 °C
• 精确质量: 236.058578
• LogP: 2.16
• InChIKey: YMNACIYZMIKRMM-UHFFFAOYSA-N
• SMILES: O=c1ccc2c3cc[nH]c4ccc(=O)n(c2c1)c43
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.796
• 水溶解性: Very slightly soluble (0.61 g/L) (25 ºC)

9-羟基铁屎米酮靶点实验

查看更多实验

实验名称：Activation of GSK-3beta in zebrafish embryo assessed as suppression of mitf gene expr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3585154

实验名称：Activation of GSK-3beta in zebrafish embryo assessed as reduction of pigment cells on... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3582543

实验名称：Induction of apoptosis in zebrafish embryo at 300 uM measured 10 to 24 hrs post ferti... 来源：ChEMBL 靶标：Danio rerio External Id：CHEMBL3584622

实验名称：Activation of GSK-3beta in zebrafish embryo assessed as suppression of zic2a gene exp... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3585153

实验名称：Activation of GSK-3beta in human SW480 cells assessed as increase in phosphorylation ... 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL3582546

实验名称：Activation of GSK-3beta in human SW480 cells assessed as increase in phosphorylation ... 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL3582547

实验名称：Activation of GSK-3beta in human SW480 cells assessed as downregulation of beta-caten... 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL3582544

实验名称：Activation of GSK-3beta in human SW480 cells assessed as downregulation of beta-caten... 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL3582545

实验名称：Effect on CK1alpha expression in human SW480 cells at 10 to 30 uM after 24 hrs by Wes... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL3582550

实验名称：Effect on GSK-3beta expression in human SW480 cells at 10 to 30 uM after 24 hrs by We... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL3582551

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9-羟基铁屎米酮英文别名

• 9-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
• 9-hydroxycanthin-6-one