水飞蓟宾B

更新时间：2025-08-25 11:35:49

水飞蓟宾B结构式	常用名	水飞蓟宾B	英文名	Silybin B
	CAS号	142797-34-0	分子量	482.436
	密度	1.5±0.1 g/cm3	沸点	793.0±60.0 °C at 760 mmHg
	分子式	C₂₅H₂₂O₁₀	熔点	158-160℃ (methanol water )
	MSDS	美版	闪点	274.5±26.4 °C

水飞蓟宾B用途

Silybin B 是从 Silybum marianum 中分离出的一种黄酮木脂素,具有抗肿瘤活性。Silybin B 是水飞蓟素最有效的抗纤维原性和抗低聚物成分,是一种有前景的抗阿尔茨海默病药物候选。

中文名	水飞蓟宾A+B
英文名	Silibinin
英文别名	更多

描述	Silybin B 是从 Silybum marianum 中分离出的一种黄酮木脂素,具有抗肿瘤活性。Silybin B 是水飞蓟素最有效的抗纤维原性和抗低聚物成分,是一种有前景的抗阿尔茨海默病药物候选。
相关类别	研究领域 >> 癌症研究领域 >> 神经疾病
参考文献	[1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738. [2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

描述

相关类别

研究领域 >> 癌症

研究领域 >> 神经疾病

参考文献

[1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738.

[2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

密度	1.5±0.1 g/cm3
沸点	793.0±60.0 °C at 760 mmHg
熔点	158-160℃ (methanol water )
分子式	C₂₅H₂₂O₁₀
分子量	482.436
闪点	274.5±26.4 °C
精确质量	482.121307
LogP	2.59
蒸汽压	0.0±2.9 mmHg at 25°C
折射率	1.684
储存条件	2-8°C

危险品运输编码	NONH for all modes of transport

Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.

Drug Metab. Dispos. 42(10) , 1675-83, (2014)

Drug-metabolizing enzymes within enterocytes constitute a key barrier to xenobiotic entry into the systemic circulation. Furanocoumarins in grapefruit juice are cornerstone examples of diet-derived xe...

Isolation and purification of diastereoisomeric flavonolignans from silymarin by binary-column recycling preparative high-performance liquid chromatography.

J. Sep. Sci. 37(17) , 2300-6, (2014)

Silymarin extracted from Silybum marianum (L.) Gaertn consists of a large number of flavonolignans, of which diastereoisomeric flavonolignans including silybin A and silybin B, and isosilybin A and is...

MFCD03225424

SILIBININ A

(2R,3R)-3,5,7-Trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one

EINECS 245-302-5

[2R-[2a,3b,6(2R*,3R*)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Silibinin

Silybin

Silybum Substance E6

33X338MNE4

MFCD00872186

Dura-Silymarin