阿扎兰司他

• 常用名: 阿扎兰司他
• 英文名: 4-({[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl]methyl}sulfanyl)aniline
• CAS号: 143393-27-5
• 分子量: 429.96300
• 密度: 1.31g/cm3
• 沸点: 647.7ºC at 760mmHg
• 分子式: C₂₂H₂₄ClN₃O₂S
• 熔点: N/A
• 闪点: 345.5ºC

阿扎兰司他名称

• 中文名: 阿扎兰司他
• 英文名: 4-({[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl]methyl}sulfanyl)aniline

阿扎兰司他物理化学性质

• 密度: 1.31g/cm3
• 沸点: 647.7ºC at 760mmHg
• 分子式: C₂₂H₂₄ClN₃O₂S
• 分子量: 429.96300
• 闪点: 345.5ºC
• 精确质量: 429.12800
• PSA: 87.60000
• LogP: 5.23670
• InChIKey: VYNIUBZKEWJOJP-UNMCSNQZSA-N
• SMILES: Nc1ccc(SCC2COC(CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)cc1
• 蒸汽压: 1.16E-16mmHg at 25°C
• 折射率: 1.644

阿扎兰司他靶点实验

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实验名称：Inhibition of Sprague-Dawley rat spleen microsome HO1 来源：ChEMBL 靶标：Heme oxygenase 1 External Id：CHEMBL905312

实验名称：Selectivity index, ratio of IC50 for inhibition of Sprague-Dawley rat brain microsome... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056452

实验名称：Inhibition of Sprague-Dawley rat brain microsome HO2 来源：ChEMBL 靶标：Heme oxygenase 2 External Id：CHEMBL905313

实验名称：Selectivity index, ratio of IC50 for Sprague-Dawley rat brain HO2 to IC50 for Sprague... 来源：ChEMBL 靶标：N/A External Id：CHEMBL905314

实验名称：Effect on total serum cholesterol in male hamsters at a dose of 10 mg/kg orally admin... 来源：ChEMBL 靶标：Cricetinae gen. sp. External Id：CHEMBL692826

实验名称：Effect on total serum cholesterol in male hamsters at a dose of 10 mg/kg orally admin... 来源：ChEMBL 靶标：Cricetinae gen. sp. External Id：CHEMBL689401

实验名称：In vitro inhibitory concentration against heme oxygenase 2 from rat brain 来源：ChEMBL 靶标：Heme oxygenase 2 External Id：CHEMBL827964

实验名称：Effect on total serum cholesterol in male hamsters at a dose of 100 mg/kg orally admi... 来源：ChEMBL 靶标：Cricetinae gen. sp. External Id：CHEMBL692828

实验名称：Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formatio... 来源：ChEMBL 靶标：Heme oxygenase 1 External Id：CHEMBL5056450

实验名称：Human CYP19A1 (CYP11, CYP17, CYP19, CYP20 and CYP21 families) 来源：IUPHAR-DB 靶标：CYP19A1 (CYP11, CYP17, CYP19, CYP20 and CYP21 families) [Homo sapiens] External Id：1362_Human

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阿扎兰司他英文别名

• (2S,4S)-6-Fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylic acid 2-propyl ester
• (2S,4S)-azalanstat
• (2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-[{(4-aminophenyl)thio}methyl]-1,3-dioxolane
• (2S,4S)-Propyl 6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylate
• (2S,4S)-cis-2-(2-(4-chlorophenyl)ethyl)-2-(imidazol-1-yl)methyl-4-(4-aminophenylthio)methyl-1,3-dioxolane
• (2S,4S)-6-fluoro-2,3-dihydro-2',5'-dioxospiro<4H-1-benzopyran-4,4'-imidazolidine>-2-carboxylic acid n-propyl ester
• (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylic acid n-propyl ester
• Azetrenatat