盐酸司来吉兰结构式
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常用名 | 盐酸司来吉兰 | 英文名 | Selegiline HCl |
|---|---|---|---|---|
| CAS号 | 14611-52-0 | 分子量 | 223.742 | |
| 密度 | 0.954g/cm3 | 沸点 | 272.5ºC at 760mmHg | |
| 分子式 | C13H18ClN | 熔点 | 141-142ºC | |
| MSDS | 中文版 美版 | 闪点 | 108.4ºC |
盐酸司来吉兰用途R-(-)-Deprenyl盐酸盐是不可逆的MAO-B选择性抑制剂。 |
| 中文名 | 盐酸司来吉兰 |
|---|---|
| 英文名 | selegiline hydrochloride |
| 中文别名 | 盐酸丙炔苯并胺 | (R)-N,alpha-二甲基-N-(2-丙炔基)苯乙胺盐酸盐 |
| 英文别名 | 更多 |
| 密度 | 0.954g/cm3 |
|---|---|
| 沸点 | 272.5ºC at 760mmHg |
| 熔点 | 141-142ºC |
| 分子式 | C13H18ClN |
| 分子量 | 223.742 |
| 闪点 | 108.4ºC |
| 精确质量 | 223.112778 |
| PSA | 3.24000 |
| LogP | 2.98460 |
| InChIKey | IYETZZCWLLUHIJ-UTONKHPSSA-N |
| SMILES | C#CCN(C)C(C)Cc1ccccc1.Cl |
| 外观性状 | 白色结晶固体 |
| 储存条件 | Store at RT |
| 水溶解性 | H2O: >10 mg/mL |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 安全声明 (欧洲) | S22-S26 |
| 危险品运输编码 | UN 3249 |
| WGK德国 | 3 |
| RTECS号 | DA0292500 |
| 包装等级 | III |
| 危险类别 | 6.1(b) |
| 海关编码 | 2921519090 |
| 盐酸司来吉兰上游产品 0 | |
|---|---|
| 盐酸司来吉兰下游产品 2 | |
| 海关编码 | 2921519090 |
|---|---|
| 中文概述 | 2921519090. 间-、对-苯二胺、二氨基甲苯等〔包括衍生物及它们的盐〕. 增值税率:17.0%. 退税率:17.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities, Molecular Docking Studies and Crystal Structure of Xanthomicrol.
Molecules 20 , 7454-73, (2015) The inhibitory effects of flavonoids on monoamine oxidases (MAOs) have attracted great interest since alterations in monoaminergic transmission are reported to be related to neurodegenerative diseases... |
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[Liver monoamine oxidase activity of the lamprey Lampetra fluviatilis. the substrate-inhibitory specificity].
Zh. Evol. Biokhim. Fiziol. 49(1) , 39-43, (2013) Based on data of substrate-inhibitory analysis with use of specific inhibitors--deprenyl, chlorgi-lin--and specific substrates--serotonin, noradrenalin, benzylamine, beta-phenylethylamine, and N-methy... |
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Modulations of brain amines and dopaminergic behavior by a novel, reversible and selective MAO-B inhibitor.
Brain Res. 1470 , 45-51, (2012) Monoamine oxidase (MAO) B is a validated target for many neurodegenerative diseases. Recently we have reported a few pyrazolines as reversible and selective MAO-B inhibitors. Amongst them, we have sel... |
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实验名称:Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源:NCGC
External Id:SNCA-p-activity-luciferase
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
来源:824
External Id:CYP273
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
来源:NCGC
External Id:HERG01
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实验名称:uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
来源:Burnham Center for Chemical Genomics
靶标:cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id:SBCCG-A764-CF-PAF-Primary-Assay
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ant...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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实验名称:Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
来源:NCGC
External Id:APP-Toga-CHIKV-nsp2-p
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| N-Methyl-N-[(2R)-1-phenyl-2-propanyl]-2-propyn-1-amine hydrochloride (1:1) |
| (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride |
| N-Methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine hydrochloride (1:1) |
| MFCD00069299 |
| (-)-(R)-N,α-Dimethyl-N-2-propynylphenethylamine monohydrochloride |
| (-)-Deprenyl hydrochloride |
| N-méthyl-N-[(1R)-1-méthyl-2-phényléthyl]prop-2-yn-1-amine chlorhydrate |
| benzeneethanamine, N,α-dimethyl-N-2-propynyl-, (αR)-, hydrochloride |
| (-)-Deprenil hydrochloride |
| selegiline hydrochloride |
| (R)-(-)-Deprenyl hydrochloride |
| R-(−)-Deprenyl hydrochloride |
| benzeneethanamine, N,a-dimethyl-N-2-propyn-1-yl-, (aR)-, hydrochloride (1:1) |
| (R)-(−)-N,α-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride |
| N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine hydrochloride |
| (-)-(R)-N,α-Dimethyl-N-2-propynylphenethylamine hydrochloride |
| N-methyl-N-[(1R)-1-methyl-2-phenylethyl]prop-2-yn-1-amine hydrochloride |
| Selegiline HCl |
| N-Methyl-N-[(1R)-1-methyl-2-phenylethyl]prop-2-in-1-aminhydrochlorid |
| (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine,hydrochloride |
| (R)-selegiline hydrochloride |
| Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-, (αR)-, hydrochloride (1:1) |
| R-(-)-Deprenyl (hydrochloride) |