氟阿尼酮

• 常用名: 氟阿尼酮
• 英文名: fluanisone
• CAS号: 1480-19-9
• 分子量: 356.434
• 密度: 1.1±0.1 g/cm3
• 沸点: 511.8±50.0 °C at 760 mmHg
• 分子式: C₂₁H₂₅FN₂O₂
• 熔点: 67.5-68.5°
• 闪点: 263.3±30.1 °C

氟阿尼酮用途

Fluanisone is a typical antipsychotic and sedative of the butyrophenone chemical class. It is used in the treatment of schizophrenia and mania. It is also a component (along with fentanyl) of the injectable veterinary formulation fentanyl/fluanisone (Hypnorm) where it is used for rodent analgesia during short surgical procedures.

氟阿尼酮名称

• 中文名: 氟苯丙酮哌嗪
• 英文名: 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
• 中文别名: 氟阿尼酮

氟阿尼酮物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 511.8±50.0 °C at 760 mmHg
• 熔点: 67.5-68.5°
• 分子式: C₂₁H₂₅FN₂O₂
• 分子量: 356.434
• 闪点: 263.3±30.1 °C
• 精确质量: 356.190002
• PSA: 32.78000
• LogP: 3.43
• InChIKey: IRYFCWPNDIUQOW-UHFFFAOYSA-N
• SMILES: COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1
• 外观性状: 固体
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.558
• 储存条件: -20°C
• 计算化学:

  1.疏水参数计算参考值（XlogP）:3.6

  2.氢键供体数量:0

  3.氢键受体数量:5

  4.可旋转化学键数量:7

  5.互变异构体数量:2

  6.拓扑分子极性表面积:32.8

  7.重原子数量:26

  8.表面电荷:0

  9.复杂度:432

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

氟阿尼酮毒性和生态

氟阿尼酮安全信息

• 海关编码: 2933599090

氟阿尼酮海关

• 海关编码: 2933599090
• 中文概述: 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

氟阿尼酮靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Suppression of aggressive behavior, after 1 hour of peroral administration in mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL736134

实验名称：Suppression of aggressive behavior, after 5 hour of peroral administration in mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL736135

实验名称：Activity calculated as Na+ ratio [IC50 (+Na+) / IC50 (-Na+)] 来源：ChEMBL 靶标：N/A External Id：CHEMBL845721

实验名称：Confirmed allosteric antagonists of M1 Muscarinic receptor 来源：1043 靶标：Muscarinic acetylcholine receptor M1 External Id：SAID_435034

实验名称：Suppression of conditioned avoidance behavior in rats after ip administration 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL883301

实验名称：Suppression of conditioned avoidance behavior in rats following p.o. administration. 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL779018

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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氟阿尼酮英文别名

• Anti-Pica
• 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)-piperazine-1-yl]butan-1-one
• Haloanisone
• N1-(2-Methoxy-phenyl)-N4-<3-(4-fluor-benzoyl)-propyl>-piperazin
• 1-(4-fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one
• MD 2028
• 4'-fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone
• Fluanisonum [INN-Latin]
• 1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-1-butanone
• Sedalande
• Fluanison
• Metorin
• 4-[4-(o-Methoxyphenyl)-1-piperazinyl]-p-fluorobutyrophenone
• 1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
• fluanisone
• Haloanison