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SB 204070

更新时间:2026-02-18 16:22:22

SB 204070结构式
SB 204070结构式
品牌特惠专场
常用名 SB 204070 英文名 SB 204070
CAS号 148688-01-1 分子量 419.34
密度 N/A 沸点 N/A
分子式 C19H28Cl2N2O4 熔点 N/A
MSDS N/A 闪点 N/A

 SB 204070用途


SB 204070 是一种高效选择性5-HT4受体拮抗剂。SB 204070 可阻断毒蕈碱受体和钠通道。SB 204070 能够用于5-HT4受体功能评估的研究。

 SB 204070名称

英文名 (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-2,3-dihydro-1,4-be nzodioxine-5-carboxylate hydrochloride (1:1)

 SB 204070生物活性

描述 SB 204070 是一种高效选择性5-HT4受体拮抗剂。SB 204070 可阻断毒蕈碱受体和钠通道。SB 204070 能够用于5-HT4受体功能评估的研究。
相关类别
参考文献

[1]. Wardle KA, et al. The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon. Br J Pharmacol. 1994 Jul;112(3):789-94.  

 SB 204070物理化学性质

分子式 C19H28Cl2N2O4
分子量 419.34
精确质量 418.14300
PSA 74.02000
LogP 4.68340
InChIKey YEQGKAOSYSXEPU-UHFFFAOYSA-N
SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1.Cl

 SB 204070靶点实验

查看更多实验

实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
实验名称:Thermal Shift Assay. Domain: start/stop: M1-L298
来源:ChEMBL
靶标:Cyclin-dependent kinase 2
External Id:CHEMBL5062802
实验名称:Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1266185
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:Thermal Shift Assay. Domain: start/stop: G861-E979
来源:ChEMBL
靶标:Transcription intermediary factor 1-alpha
External Id:CHEMBL5068426
实验名称:Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
来源:Broad Institute
靶标:N/A
External Id:7124-01_Inhibitor_SinglePoint_HTS_Activity
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
实验名称:PDSP Secondary Binding target: ADRA2A - Compounds are tested at 10 uM concentration, ...
来源:ChEMBL
靶标:Alpha-2A adrenergic receptor
External Id:CHEMBL5442194
实验名称:PDSP Secondary Binding target: HTR2B - Compounds are tested at 10 uM concentration, p...
来源:ChEMBL
靶标:5-hydroxytryptamine receptor 2B
External Id:CHEMBL5442192
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