Cratoxylone

• 常用名: Cratoxylone
• 英文名: Cratoxylone
• CAS号: 149155-01-1
• 分子量: 428.475
• 密度: 1.3±0.1 g/cm3
• 沸点: 674.2±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₈O₇
• 熔点: N/A
• 闪点: 231.2±25.0 °C

Cratoxylone用途

Cratoxylone 是从Cratoxylum Cochinchinense 的树皮中分离得到的,具有抗疟原虫活性。

Cratoxylone名称

• 中文名: 黄牛木酮
• 英文名: 1,3,6-Trihydroxy-2-(3-hydroxy-3-methylbutyl)-7-methoxy-8-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one

Cratoxylone生物活性

• 描述: Cratoxylone 是从Cratoxylum Cochinchinense 的树皮中分离得到的,具有抗疟原虫活性。
• 相关类别:
  信号通路 >> 抗感染 >> 寄生物
  研究领域 >> 感染
• 参考文献:

  [1]. Graham J.Bennett, et al. Triterpenoids, tocotrienols and xanthones from the bark of Cratoxylum Cochinchinense. Phytochemistry. Volume 32, Issue 5, March 1993, Pages 1245-1251.

  [2]. Lenta BN, et al. Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea. Planta Med. 2011 Mar;77(4):377-9.

Cratoxylone物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 674.2±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₈O₇
• 分子量: 428.475
• 闪点: 231.2±25.0 °C
• 精确质量: 428.183502
• LogP: 3.71
• InChIKey: JSXIWUDODLMCGG-UHFFFAOYSA-N
• SMILES: COc1c(O)cc2oc3cc(O)c(CCC(C)(C)O)c(O)c3c(=O)c2c1CC=C(C)C
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.625
• 储存条件: 2-8°C，密封，干燥

Cratoxylone靶点实验

查看更多实验

实验名称：Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured fo... 来源：ChEMBL 靶标：Maltase-glucoamylase External Id：CHEMBL4187356

实验名称：Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon pl... 来源：ChEMBL 靶标：Maltase-glucoamylase External Id：CHEMBL4187357

实验名称：Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia co... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4187358

实验名称：Inhibition of alpha-glucosidase (unknown origin) at > 100 uM using p-nitrophenyl alph... 来源：ChEMBL 靶标：Maltase-glucoamylase External Id：CHEMBL4344047

实验名称：Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells incubated for 24 h... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4344044

实验名称：Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia co... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4187359

实验名称：Mixed type inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate ... 来源：ChEMBL 靶标：Maltase-glucoamylase External Id：CHEMBL4187361

实验名称：Competitive inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Es... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4187362

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Cratoxylone英文别名

• 1,3,6-Trihydroxy-2-(3-hydroxy-3-methylbutyl)-7-methoxy-8-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one