BMS-983970

• 常用名: BMS-983970
• 英文名: BMS-983970
• CAS号: 1584713-87-0
• 分子量: 518.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₆F₄N₄O₃
• 熔点: N/A
• 闪点: N/A

BMS-983970用途

BMS-983970是Notch口服性抑制剂，用于抗癌研究。

BMS-983970名称

• 中文名: BMS-983970
• 英文名: BMS-983970

BMS-983970生物活性

• 描述: BMS-983970是Notch口服性抑制剂,用于抗癌研究。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> Notch
  研究领域 >> 癌症
• 参考文献:

  [1]. Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer. Cancer Res October 1, 2014 74; 1643

BMS-983970物理化学性质

• 分子式: C₂₆H₂₆F₄N₄O₃
• 分子量: 518.5
• InChIKey: RANYIWAZSQWERN-WLENULPWSA-N
• SMILES: NC(=O)C(CC1CC1)C(CCC(F)(F)F)C(=O)NC1N=C(c2ccccc2)c2cccc(F)c2NC1=O
• 储存条件: 2-8℃

BMS-983970靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-SW13-72hr

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-H295R-72hr

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

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