灰毡毛忍冬素G

• 常用名: 灰毡毛忍冬素G
• 英文名: 3,5-Di-O-caffeoylquinic acid methyl ester
• CAS号: 159934-13-1
• 分子量: 530.48
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₆O₁₂
• 熔点: N/A
• 闪点: N/A

灰毡毛忍冬素G用途

Macranthoin G 是 p38 MAPK 的抑制剂。Macranthoin G 通过下调 p38 MAPK 来保护 Aβ 或过氧化氢诱导的神经元细胞毒性。Macranthoin G 可用于阿尔茨海默病的研究。

灰毡毛忍冬素G名称

• 中文名: 3,5-O-二咖啡酰基奎宁酸甲酯
• 英文名: 3,5-Di-O-caffeoylquinic methyl ester

灰毡毛忍冬素G生物活性

• 描述: Macranthoin G 是 p38 MAPK 的抑制剂。Macranthoin G 通过下调 p38 MAPK 来保护 Aβ 或过氧化氢诱导的神经元细胞毒性。Macranthoin G 可用于阿尔茨海默病的研究。
• 相关类别:
  信号通路 >> MAPK/ERK信号通路 >> p38 MAPK
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Lee JK, et al. Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease. Molecules. 2017 Aug 2;22(8):1287.

灰毡毛忍冬素G物理化学性质

• 分子式: C₂₆H₂₆O₁₂
• 分子量: 530.48
• InChIKey: VEBNYMXKXIIGFX-IYVYCCGLSA-N
• SMILES: COC(=O)C1(O)CC(OC(=O)C=Cc2ccc(O)c(O)c2)C(O)C(OC(=O)C=Cc2ccc(O)c(O)c2)C1
• 外观性状: 粉末
• 储存条件: 2-8℃

灰毡毛忍冬素G靶点实验

查看更多实验

实验名称：Inhibition of RANKL-mediated decrease in Mafb mRNA expression in ICR mouse BMDM at 5 ... 来源：ChEMBL 靶标：BMDM External Id：CHEMBL4121925

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3379704

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3379703

实验名称：Inhibition of RANKL-mediated decrease in Irf8 mRNA expression in ICR mouse BMDM at 5 ... 来源：ChEMBL 靶标：BMDM External Id：CHEMBL4121923

实验名称：Inhibition of RANKL-mediated decrease in Bcl6 mRNA expression in ICR mouse BMDM at 5 ... 来源：ChEMBL 靶标：BMDM External Id：CHEMBL4121924

实验名称：Inhibition of RANKL-induced ERK phosphorylation in ICR mouse BMDM at 5 uM preincubate... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4121921

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1944398

实验名称：Inhibition of PTP1B (unknown origin) 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4189096

实验名称：Inhibition of RANKL-induced AKT phosphorylation in ICR mouse BMDM at 5 uM preincubate... 来源：ChEMBL 靶标：RAC-alpha serine/threonine-protein kinase External Id：CHEMBL4121922

实验名称：Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1944397

共44条，当前第1页，共5页

1

2

3

4

5