Glyoxalase I inhibitor 1

• 常用名: Glyoxalase I inhibitor 1
• 英文名: Glyoxalase I inhibitor 1
• CAS号: 1622952-07-1
• 分子量: 586.64
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₂₇FN₆O₄S
• 熔点: N/A
• 闪点: N/A

Glyoxalase I inhibitor 1用途

乙二醛酶I抑制剂1(化合物23)是一种有效的乙二醛酶I(GLO1)抑制剂,IC50为26 nM【1】。

Glyoxalase I inhibitor 1名称

• 英文名: Glyoxalase I inhibitor 1

Glyoxalase I inhibitor 1生物活性

• 描述: 乙二醛酶I抑制剂1(化合物23)是一种有效的乙二醛酶I(GLO1)抑制剂,IC50为26 nM【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 靶点实验:

  IC50: 26 nM µM (GLO1)[1]

• 参考文献:

  [1]. Jin T, Zhao L, et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28(4):115243.

Glyoxalase I inhibitor 1物理化学性质

• 分子式: C₃₀H₂₇FN₆O₄S
• 分子量: 586.64

Glyoxalase I inhibitor 1靶点实验

查看更多实验

实验名称：Induction of apoptosis in human HeLa cells under high glucose condition assessed as n... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3224387

实验名称：Inhibition of GLO-1 in human HeLa cells under high glucose condition assessed as incr... 来源：ChEMBL 靶标：Lactoylglutathione lyase External Id：CHEMBL3224389

实验名称：Induction of apoptosis in human HeLa cells under high glucose condition assessed as c... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3224388

实验名称：Growth inhibition of human A549 cells after 48 hrs by CellTiter-Glo assay in presence... 来源：ChEMBL 靶标：A549 External Id：CHEMBL3224391

实验名称：Growth inhibition of human HeLa cells after 48 hrs by CellTiter-Glo assay in presence... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3224393

实验名称：Growth inhibition of human A549 cells after 48 hrs by CellTiter-Glo assay in presence... 来源：ChEMBL 靶标：A549 External Id：CHEMBL3224392

实验名称：Growth inhibition of human NCI-H522 cells after 48 hrs by CellTiter-Glo assay in pres... 来源：ChEMBL 靶标：NCI-H522 External Id：CHEMBL3224395

实验名称：Growth inhibition of human HeLa cells after 48 hrs by CellTiter-Glo assay in presence... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3224394

实验名称：Inhibition of recombinant GLO-1 (unknown origin) assessed as S-D-lactoylglutathione f... 来源：ChEMBL 靶标：Lactoylglutathione lyase External Id：CHEMBL3224397

实验名称：Growth inhibition of human NCI-H522 cells after 48 hrs by CellTiter-Glo assay in pres... 来源：ChEMBL 靶标：NCI-H522 External Id：CHEMBL3224396

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