卡泊芬净

• 常用名: 卡泊芬净
• 英文名: Caspofungin
• CAS号: 162808-62-0
• 分子量: 1092.33000
• 密度: 1.36g/cm3
• 沸点: 1408.1ºC at 760mmHg
• 分子式: C₅₃H₈₉N₉O₁₅
• 熔点: N/A
• 闪点: 805.4ºC

卡泊芬净用途

卡泊芬净是一种有效的抗真菌剂。卡泊芬净抑制真菌细胞壁成分β-(l,3)-D-葡聚糖的合成[1][2]。

卡泊芬净名称

• 中文名: 卡泊芬净
• 英文名: caspofungin

卡泊芬净生物活性

• 描述: 卡泊芬净是一种有效的抗真菌剂。卡泊芬净抑制真菌细胞壁成分β-(l,3)-D-葡聚糖的合成[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 参考文献:

  [1]. Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7.

  [2]. Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5796-803.

卡泊芬净物理化学性质

• 密度: 1.36g/cm3
• 沸点: 1408.1ºC at 760mmHg
• 分子式: C₅₃H₈₉N₉O₁₅
• 分子量: 1092.33000
• 闪点: 805.4ºC
• 精确质量: 1091.65000
• PSA: 400.00000
• LogP: 0.76120
• InChIKey: JYIKNQVWKBUSNH-FMIIYRCSSA-N
• SMILES: CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(NCCN)NC(=O)C2C(O)CCN2C(=O)C(C(O)CCN)NC(=O)C(C(O)C(O)c2ccc(O)cc2)NC(=O)C2CC(O)CN2C(=O)C(C(C)O)NC1=O
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.623
• 储存条件: 2-8°C

卡泊芬净靶点实验

查看更多实验

实验名称：Antifungal activity against Candida krusei ATCC 6258 measured after 48 hrs by CLSI M2... 来源：ChEMBL 靶标：Pichia kudriavzevii External Id：CHEMBL4413261

实验名称：Antifungal activity against Candida parapsilosis ATCC 22019 measured after 48 hrs by ... 来源：ChEMBL 靶标：Candida parapsilosis External Id：CHEMBL4413262

实验名称：Antifungal activity against Aspergillus flavus ATCC MYA-3631 measured after 48 hrs by... 来源：ChEMBL 靶标：Aspergillus flavus External Id：CHEMBL4413263

实验名称：Antifungal activity against Aspergillus nidulans ATCC 38163 measured after 48 hrs by ... 来源：ChEMBL 靶标：Aspergillus nidulans External Id：CHEMBL4413264

实验名称：Antifungal activity against Aspergillus terreus ATCC MYA-3633 measured after 48 hrs b... 来源：ChEMBL 靶标：Aspergillus terreus External Id：CHEMBL4413265

实验名称：Antifungal activity against fluconazole/ITC-resistant Candida albicans ATCC 10231 mea... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4413253

实验名称：Antifungal activity against fluconazole/ITC-resistant Candida albicans ATCC 64124 mea... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4413254

实验名称：Antifungal activity against fluconazole/ITC-susceptible Candida albicans ATCC MYA-287... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4413255

实验名称：Antifungal activity against fluconazole/ITC-resistant Candida albicans ATCC 90819 mea... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4413256

实验名称：Antifungal activity against fluconazole/ITC-susceptible Candida albicans ATCC MYA-231... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4413257

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卡泊芬净英文别名

• Caspofungin
• m991
• PORFUNGIN
• POFUNGIN