PARP1-IN-6

更新时间：2025-11-26 21:05:18

PARP1-IN-6用途

PARP1-IN-6是一种双管蛋白/PARP-1抑制剂,IC50值分别为0.94和0.48μM。

英文名	PARP1-IN-6

描述	PARP1-IN-6是一种双管蛋白/PARP-1抑制剂,IC50值分别为0.94和0.48μM。
相关类别	研究领域 >> 癌症信号通路 >> 表观遗传学 >> PARP 信号通路 >> 细胞周期/DNA损伤 >> PARP
参考文献	[1]. Zheng L, et al. Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. J Med Chem. 2021 Nov 11;64(21):15702-15715.

分子式	C₁₆H₁₁FN₂O
分子量	266.27

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as effect o...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242979

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as effect o...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242978

实验名称：Hepatotoxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as ef...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242981

实验名称：Hepatotoxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as ef...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242980

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as change i...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242975

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as change i...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242974

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as effect o...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242977

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as effect o...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242976

实验名称：Toxicity in BALB/c mouse xenografted with human MDA-MB-231 cells assessed as increase...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5242971

实验名称：Anticancer activity against human MDA-MB-231 cells xenografted in BALB/c mouse assess...
来源：ChEMBL
靶标：MDA-MB-231
External Id：CHEMBL5242970

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