3-(4-甲基苯基磺酰胺基)苯甲酸甲酯

• 常用名: 3-(4-甲基苯基磺酰胺基)苯甲酸甲酯
• 英文名: MSAB
• CAS号: 173436-66-3
• 分子量: 305.349
• 密度: 1.3±0.1 g/cm3
• 沸点: 456.5±55.0 °C at 760 mmHg
• 分子式: C₁₅H₁₅NO₄S
• 熔点: 152-154°C
• 闪点: 229.9±31.5 °C

3-(4-甲基苯基磺酰胺基)苯甲酸甲酯用途

MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.

3-(4-甲基苯基磺酰胺基)苯甲酸甲酯名称

• 中文名: 3-(4-甲基苯基磺酰胺基)苯甲酸甲酯
• 英文名: MSAB

3-(4-甲基苯基磺酰胺基)苯甲酸甲酯物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 456.5±55.0 °C at 760 mmHg
• 熔点: 152-154°C
• 分子式: C₁₅H₁₅NO₄S
• 分子量: 305.349
• 闪点: 229.9±31.5 °C
• 精确质量: 305.072174
• LogP: 1.04
• InChIKey: CVKBYFCJQSPBOI-UHFFFAOYSA-N
• SMILES: COC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.600
• 储存条件: 2-8°C

3-(4-甲基苯基磺酰胺基)苯甲酸甲酯安全信息

• 危害码 (欧洲): Xi

3-(4-甲基苯基磺酰胺基)苯甲酸甲酯靶点实验

查看更多实验

实验名称：Thermal stabilization of wildtype beta catenin ARD (148 to 662 residues) (unknown ori... 来源：ChEMBL 靶标：Catenin beta-1 External Id：CHEMBL5105271

实验名称：Anticancer activity against human HCT-116 cells assessed as reduction in cell viabili... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5226915

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

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3-(4-甲基苯基磺酰胺基)苯甲酸甲酯英文别名

• 3-(Toluene-4-sulfonylamino)-benzoic acid methyl ester
• 3-[[(4-Methylphenyl)sulfonyl]amino]-benzoic acid methyl ester
• Benzoic acid, 3-[[(4-methylphenyl)sulfonyl]amino]-, methyl ester
• MFCD00994918