3’-β-C-Ethynyladenosine

• 常用名: 3’-β-C-Ethynyladenosine
• 英文名: 3’-β-C-Ethynyladenosine
• CAS号: 180300-54-3
• 分子量: 291.26
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₂H₁₃N₅O₄
• 熔点: N/A
• 闪点: N/A

3’-β-C-Ethynyladenosine用途

3'-β-丙炔基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。其受欢迎的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。

3’-β-C-Ethynyladenosine名称

• 英文名: 3’-β-C-Ethynyladenosine

3’-β-C-Ethynyladenosine生物活性

• 描述: 3'-β-丙炔基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。其受欢迎的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物
• 参考文献:

  [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

  [2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

3’-β-C-Ethynyladenosine物理化学性质

• 分子式: C₁₂H₁₃N₅O₄
• 分子量: 291.26
• InChIKey: VVIJADJDBPHCKC-WHNOBIIHSA-N
• SMILES: C#CC1(O)C(CO)OC(n2cnc3c(N)ncnc32)C1O

3’-β-C-Ethynyladenosine靶点实验

查看更多实验

实验名称：Antiproliferative activity against mouse L1210 cells after 48 hrs by Coulter counter ... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL4274354

实验名称：Antiproliferative activity against human HeLa cells after 72 hrs by Coulter counter m... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4274356

实验名称：Antiproliferative activity against human CEM cells after 72 hrs by Coulter counter me... 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL4274355

实验名称：Antiviral activity against Sindbis virus at 100 uM 来源：ChEMBL 靶标：Sindbis virus External Id：CHEMBL3791795

实验名称：In vitro tumor cell growth inhibitory activity against mouse leukemia L1210 cell line... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL705540

实验名称：Antiviral activity against Aciclovir-resistant thymidine kinase-deficient HSV-1 KOS a... 来源：ChEMBL 靶标：Human alphaherpesvirus 1 External Id：CHEMBL3791799

实验名称：Cytostatic activity against human HeLa cells after 72 hrs by Coulter counter method 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3791796

实验名称：Antiviral activity against Human cytomegalovirus Davis strain infected in HELF cells ... 来源：ChEMBL 靶标：Human betaherpesvirus 5 External Id：CHEMBL4274721

实验名称：Antiviral activity against thymidine kinase-deficient Varicella Zoster virus Oka stra... 来源：ChEMBL 靶标：Human alphaherpesvirus 3 External Id：CHEMBL4274718

实验名称：Cytotoxicity against HELF cells after by Coulter counter method 来源：ChEMBL 靶标：N/A External Id：CHEMBL4274717

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