8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯

• 常用名: 8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯
• 英文名: 8α-(2-Methylacryloyloxy)hirsutinolide
• CAS号: 188293-70-1
• 分子量: 364.390
• 密度: 1.3±0.1 g/cm3
• 沸点: 583.7±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₄O₇
• 熔点: N/A
• 闪点: 208.5±23.6 °C

8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯名称

• 中文名: 2-甲基-2-丙烯酸 (4S,6R,7S,10R)-2,4,5,6,7,8,9,10-八氢-7-羟基-3-(羟基甲基)-6,10-二甲基-2-氧代-7,10-环氧(11E)-环癸[B]呋喃-4-基酯
• 英文名: (1R,2E,8S,10R,11S)-11-Hydroxy-6-(hydroxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl methacrylate

8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 583.7±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₄O₇
• 分子量: 364.390
• 闪点: 208.5±23.6 °C
• 精确质量: 364.152191
• LogP: 2.28
• InChIKey: VSNXXZXCVFUXKD-LYUOXOCJSA-N
• SMILES: C=C(C)C(=O)OC1CC(C)C2(O)CCC(C)(C=C3OC(=O)C(CO)=C31)O2
• 外观性状: 粉末
• 蒸汽压: 0.0±3.7 mmHg at 25°C
• 折射率: 1.576
• 储存条件: 2-8℃

8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯安全信息

• 危害码 (欧洲): Xi

8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse NIH/3T3 cells at 5uM after 72 hrs by cyquant cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL3630190

实验名称：Antiproliferative activity against human SF295 cells at 5 uM for 72 hrs by cyquant as... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3630189

实验名称：Antiproliferative activity against human MDA-MB-231 cells at 5 uM for 72 hrs by cyqua... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL3630188

实验名称：Inhibition of Stat3 dimer DNA binding activity in mouse NIH3T3/vSrc nuclear extract a... 来源：ChEMBL 靶标：Signal transducer and activator of transcription 3 External Id：CHEMBL3632013

实验名称：Inhibition of Stat1 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear... 来源：ChEMBL 靶标：Signal transducer and activator of transcription 1 External Id：CHEMBL3632018

实验名称：Inhibition of Stat5 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3632017

实验名称：Inhibition of Stat3 activity in human U251MG cells assessed as phosphorylated Stat3 l... 来源：ChEMBL 靶标：Signal transducer and activator of transcription 3 External Id：CHEMBL3632028

实验名称：Antiproliferative activity against human U251MG cells at 5 uM for 72 hrs by cyquant a... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3630077

共8条，当前第1页，共1页

1

8α-(2-甲基丙烯酰氧基)硬毛钩藤内酯英文别名

• (1R,2E,8S,10R,11S)-11-Hydroxy-6-(hydroxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl methacrylate
• 2-Propenoic acid, 2-methyl-, (4S,6R,7S,10R,11E)-2,4,5,6,7,8,9,10-octahydro-7-hydroxy-3-(hydroxymethyl)-6,10-dimethyl-2-oxo-7,10-epoxycyclodeca[b]furan-4-yl ester