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8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione

更新时间:2025-08-26 17:00:22

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式
8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式
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常用名 8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione 英文名 8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione
CAS号 18903-26-9 分子量 183.18800
密度 1.522g/cm3 沸点 N/A
分子式 C6H5N3O2S 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 2-methyl-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione
英文别名 更多

 物理化学性质

密度 1.522g/cm3
分子式 C6H5N3O2S
分子量 183.18800
精确质量 183.01000
PSA 106.85000
InChIKey MZOFKOXXOSTFHL-UHFFFAOYSA-N
SMILES Cc1nc2[nH]c(=O)[nH]c(=O)c2s1
折射率 1.616

 合成线路

~90%

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式

8-methyl-7-thia...

18903-26-9

文献:F.HOFFMANN-LA ROCHE AG Patent: WO2008/152390 A1, 2008 ; Location in patent: Page/Page column 33; 49 ; WO 2008/152390 A1

~99%

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式

8-methyl-7-thia...

18903-26-9

文献:F.HOFFMANN-LA ROCHE AG Patent: WO2008/152390 A1, 2008 ; Location in patent: Page/Page column 49 ; WO 2008/152390 A1

~%

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式

8-methyl-7-thia...

18903-26-9

文献:Childress; McKee Journal of the American Chemical Society, 1951 , vol. 73, p. 3862

~%

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式

8-methyl-7-thia...

18903-26-9

文献:Bauer,L.; Mahajanshetti,C.S. Journal of Heterocyclic Chemistry, 1968 , vol. 5, p. 331 - 335

~%

8-methyl-7-thia-2,4,9-triazabicyclo[4.3.0]nona-8,10-diene-3,5-dione结构式

8-methyl-7-thia...

18903-26-9

文献:Bauer,L.; Mahajanshetti,C.S. Journal of Heterocyclic Chemistry, 1968 , vol. 5, p. 331 - 335

 靶点实验

查看更多实验

实验名称:Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:HCMV UL50
External Id:HMS1262
实验名称:Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:ORF 73 [Human herpesvirus 8 type M]
External Id:HMS791
实验名称:High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS1303
实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
实验名称:A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:Chain A, Poliovirus Polymerase With Gtp
External Id:HMS750
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 英文别名

2-methyl-thiazolo[5,4-e]pyrimidine-5,7-diol
HMS1607O06
2-Methyl-thiazolo<4.5-d>pyrimidin-5,7-(4H,6H)-dion
2-methyl-4H-thiazolo[4,5-d]pyrimidine-5,7-dione
2-Methyl-4H-thiazolo[4,5-d]pyrimidin-5,7-dion
2-methylthiazolo<4,5-d>pyrimidine-5,7-dione
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