KDM5A-IN-1

• 常用名: KDM5A-IN-1
• 英文名: KDM5A-IN-1
• CAS号: 1905481-36-8
• 分子量: 290.361
• 密度: 1.3±0.1 g/cm3
• 沸点: 592.6±50.0 °C at 760 mmHg
• 分子式: C₁₅H₂₂N₄O₂
• 熔点: N/A
• 闪点: 312.2±30.1 °C

KDM5A-IN-1用途

KDM5A-IN-1是组蛋白去甲基化酶抑制剂。

KDM5A-IN-1名称

• 中文名: KDM5A-IN-1
• 英文名: KDM5A-IN-1

KDM5A-IN-1生物活性

• 描述: KDM5A-IN-1是组蛋白去甲基化酶抑制剂。
• 相关类别:
  信号通路 >> 表观遗传学 >> 组蛋白去甲基化酶
  研究领域 >> 癌症
• 参考文献:

  [1]. Kwong Wah LAI, et al. Pyrrolidine amide compounds as histone demethylase inhibitors. PCT Int. Appl. (2016), WO 2016057924 A1 20160414.

KDM5A-IN-1物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 592.6±50.0 °C at 760 mmHg
• 分子式: C₁₅H₂₂N₄O₂
• 分子量: 290.361
• 闪点: 312.2±30.1 °C
• 精确质量: 290.174286
• LogP: -1.13
• InChIKey: CXEXTVGTDZRKJS-LLVKDONJSA-N
• SMILES: CC(C)c1cc(C(=O)N2CCC(NC(=O)C3CC3)C2)n[nH]1
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.586
• 储存条件: 2-8℃

KDM5A-IN-1靶点实验

查看更多实验

实验名称：Inhibition of KDM6 in human MCF7 cells assessed as increase in H3K27me3 level up to 1... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024516

实验名称：NCATS Kinetic Aqueous Solubility Profiling 来源：NCGC 靶标：N/A External Id：ADME-solubility1

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Inhibition of KDM6 in human SK-BR-3 cells assessed as increase in H3K27me3 level up t... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024514

实验名称：Inhibition of KDM6 in human BT474 cells assessed as increase in H3K27me3 level up to ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024515

实验名称：Inhibition of KDM4 in human BT474 cells assessed as increase in H3K9me3 level up to 1... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024512

实验名称：Inhibition of KDM4 in human MCF7 cells assessed as increase in H3K9me3 level up to 10... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024513

实验名称：Growth inhibition of human MDA-MB-231 cells at 0.1 to 50 uM measured every 4 hrs for ... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL4024510

实验名称：Inhibition of KDM4 in human SK-BR-3 cells assessed as increase in H3K9me3 level up to... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4024511

实验名称：NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling 来源：NCGC 靶标：N/A External Id：ADME-PAMPA1

共62条，当前第1页，共7页

1

2

3

4

5

KDM5A-IN-1英文别名

• N-{(3R)-1-[(3-Isopropyl-1H-pyrazol-5-yl)carbonyl]-3-pyrrolidinyl}cyclopropanecarboxamide