皂草苷；皂草黄苷

更新时间：2025-08-26 19:43:43

皂草苷；皂草黄苷结构式	常用名	皂草苷；皂草黄苷	英文名	Saponarin
	CAS号	20310-89-8	分子量	594.51800
	密度	1.723 g/cm3	沸点	919.5ºC at 760 mmHg
	分子式	C₂₇H₃₀O₁₅	熔点	228ºC (dec.)
	MSDS	N/A	闪点	305.4ºC

皂草苷；皂草黄苷用途

Saponarin 是一种从 Gypsophila trichotoma 中分离出的天然的黄酮类化合物,具有抗氧化、抗炎和保护肝脏的作用。Saponarin 以钙依赖的方式激活AMPK,从而调节糖异生和葡萄糖摄取。

中文名	皂草苷
英文名	7-O-(β-D-glucosyl)isovitexin
中文别名	皂草黄苷
英文别名	更多

描述	Saponarin 是一种从 Gypsophila trichotoma 中分离出的天然的黄酮类化合物,具有抗氧化、抗炎和保护肝脏的作用。Saponarin 以钙依赖的方式激活AMPK,从而调节糖异生和葡萄糖摄取。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 炎症/免疫
参考文献	[1]. Simeonova R, et al. Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine. 2016 May 15;23(5):483-90. [2]. Seo KH, et al. Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 2014 Nov;5(11):3005-13. [3]. Seo WD, et al. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5237-42.

描述

相关类别

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

参考文献

[1]. Simeonova R, et al. Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine. 2016 May 15;23(5):483-90.

[2]. Seo KH, et al. Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 2014 Nov;5(11):3005-13.

[3]. Seo WD, et al. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5237-42.

密度	1.723 g/cm3
沸点	919.5ºC at 760 mmHg
熔点	228ºC (dec.)
分子式	C₂₇H₃₀O₁₅
分子量	594.51800
闪点	305.4ºC
精确质量	594.15800
PSA	260.20000
InChIKey	HGUVPEBGCAVWID-KETMJRJWSA-N
SMILES	O=c1cc(-c2ccc(O)cc2)oc2cc(OC3OC(CO)C(O)C(O)C3O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12
外观性状	黄色粉末
蒸汽压	0mmHg at 25°C
折射率	1.728
储存条件	2-8℃

实验名称：Cell-based high throughput primary assay to identify activators of GPR151
来源：The Scripps Research Institute Molecular Screening Center
靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源：The Scripps Research Institute Molecular Screening Center
靶标：N/A
External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源：The Scripps Research Institute Molecular Screening Center
External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Agonist activity at TRPA1 (unknown origin) at 1000 uM relative to AITC
来源：ChEMBL
靶标：Transient receptor potential cation channel subfamily A member 1
External Id：CHEMBL4620421

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Saponaretin-7-O-glucoside

5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

apigenin-6-C,7-O-diglucoside

7-O-(beta-D-glucosyl)isovitexin

Saponarin

isovitexin-7-O-glucoside