银椴苷; 椴树苷结构式
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常用名 | 银椴苷; 椴树苷 | 英文名 | tiliroside |
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| CAS号 | 20316-62-5 | 分子量 | 594.520 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 943.9±65.0 °C at 760 mmHg | |
| 分子式 | C30H26O13 | 熔点 | 257-260ºC | |
| MSDS | 中文版 美版 | 闪点 | 311.9±27.8 °C |
银椴苷; 椴树苷用途Tiliroside 是一种糖苷类黄酮,具有抗糖尿病作用。Tiliroside 是 α-淀粉酶 (α-amylase) 的非竞争性抑制剂,Ki 值为 84.2 μM。Tiliroside 抑制胃肠道中碳水化合物的消化和葡萄糖的吸收。 |
| 中文名 | 银锻苷 |
|---|---|
| 英文名 | tiliroside |
| 中文别名 | 银椴苷 | 密蒙花苷 | 刺蒺藜苷 | 椴树苷 |
| 英文别名 | 更多 |
| 描述 | Tiliroside 是一种糖苷类黄酮,具有抗糖尿病作用。Tiliroside 是 α-淀粉酶 (α-amylase) 的非竞争性抑制剂,Ki 值为 84.2 μM。Tiliroside 抑制胃肠道中碳水化合物的消化和葡萄糖的吸收。 |
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| 相关类别 | |
| 体外研究 | 替罗西德体外抑制胰腺α-淀粉酶(IC50=0.28 mM)[1]。 |
| 体内研究 | 在雄性ICR小鼠中,替罗西德给药组显著抑制餐后血糖水平的升高[1]。 |
| 参考文献 |
| 密度 | 1.7±0.1 g/cm3 |
|---|---|
| 沸点 | 943.9±65.0 °C at 760 mmHg |
| 熔点 | 257-260ºC |
| 分子式 | C30H26O13 |
| 分子量 | 594.520 |
| 闪点 | 311.9±27.8 °C |
| 精确质量 | 594.137329 |
| PSA | 216.58000 |
| LogP | 3.83 |
| InChIKey | DVGGLGXQSFURLP-VWMSDXGPSA-N |
| SMILES | O=C(C=Cc1ccc(O)cc1)OCC1OC(Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)C(O)C(O)C1O |
| 蒸汽压 | 0.0±0.3 mmHg at 25°C |
| 折射率 | 1.759 |
| 储存条件 | 2-8°C |
| 危险品运输编码 | NONH for all modes of transport |
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Investigation into biologically active constituents of Geum rivale L.
Acta Pol. Pharm. 70(1) , 111-4, (2013) Aerial and underground parts of Geum rivale (Rosaceae) were investigated. Tiliroside, gallic acid, ellagic acid and a sterol fraction were isolated from aerial parts of the plant. The sterol fraction ... |
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New phenolic compounds with anti-adipogenic activity from the aerial parts of Pulsatilla koreana.
Planta Med. 78(16) , 1783-6, (2012) Three new phenolic compounds, pulsatillosides A (1), B (2), and C (3), were isolated from the aerial parts of Pulsatilla koreana, together with two known flavonoid glycosides, trans-tiliroside (4) and... |
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Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberry.
J. Enzyme Inhib. Med. Chem. 24(5) , 1154-60, (2009) Tiliroside was found to inhibit both monophenolase and diphenolase activity of mushroom tyrosinase. The lag time of tyrosine oxidation catalyzed by mushroom tyrosinase was obviously lengthened; 0.337 ... |
| 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-b-D-glucopyranoside |
| [(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl-(2E)-3-(4-hydroxyphenyl)acrylat |
| Kaempferol-3-Glucoside-6''-p-coumaroyl |
| tiliroside |
| [(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl (2E)-3-(4-hydroxyphenyl)acrylate |
| (2E)-3-(4-Hydroxyphényl)acrylate de [(2R,3S,4S,5R,6S)-6-{[5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-3-yl]oxy}-3,4,5-trihydroxytétrahydro-2H-pyran-2-yl]méthyle |
| trans-tiliroside |
| 6-O-[(2E)-3-(4-Hydroxyphényl)-2-propènan-1-oyl]-β-D-glucopyranoside de 5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-3-yle |
| 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside |
| 6'-O-trans-p-CouMaroylastragalin |
| 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside |
| 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl-6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside |