tiliroside

Modify Date: 2024-01-02 14:46:49

tiliroside structure	Common Name	tiliroside
	CAS Number	20316-62-5	Molecular Weight	594.520
	Density	1.7±0.1 g/cm3	Boiling Point	943.9±65.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₂₆O₁₃	Melting Point	257-260ºC
	MSDS	Chinese USA	Flash Point	311.9±27.8 °C

Use of tiliroside

Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a Ki value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract[1].

Name	tiliroside
Synonym	More Synonyms

Description	Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a Ki value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Tiliroside inhibits pancreatic α-amylase (IC50=0.28 mM) in vitro[1].
In Vivo	In male ICR mice, the increase in postprandial plasma glucose levels was significantly suppressed in the Tiliroside-administered group[1].
References	[1]. Goto T, et al. Tiliroside, a glycosidic flavonoid, inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract. Mol Nutr Food Res. 2012 Mar;56(3):435-45.

Density	1.7±0.1 g/cm3
Boiling Point	943.9±65.0 °C at 760 mmHg
Melting Point	257-260ºC
Molecular Formula	C₃₀H₂₆O₁₃
Molecular Weight	594.520
Flash Point	311.9±27.8 °C
Exact Mass	594.137329
PSA	216.58000
LogP	3.83
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.759
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD3375250

CHEMICAL NAME :: 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 6'-ester with 3-(beta-D-glucopyranosyloxy)-5,7- dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

CAS REGISTRY NUMBER :: 20316-62-5

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C30-H25-O13

MOLECULAR WEIGHT :: 593.55

WISWESSER LINE NOTATION :: T66 BO EVJ CR DQ& GQ IQ DO- BT6OTJ CQ DQ EQ F1OV1U1R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 40 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,401,1981

RIDADR	NONH for all modes of transport

Investigation into biologically active constituents of Geum rivale L.

Acta Pol. Pharm. 70(1) , 111-4, (2013)

Aerial and underground parts of Geum rivale (Rosaceae) were investigated. Tiliroside, gallic acid, ellagic acid and a sterol fraction were isolated from aerial parts of the plant. The sterol fraction ...

New phenolic compounds with anti-adipogenic activity from the aerial parts of Pulsatilla koreana.

Planta Med. 78(16) , 1783-6, (2012)

Three new phenolic compounds, pulsatillosides A (1), B (2), and C (3), were isolated from the aerial parts of Pulsatilla koreana, together with two known flavonoid glycosides, trans-tiliroside (4) and...

Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberry.

J. Enzyme Inhib. Med. Chem. 24(5) , 1154-60, (2009)

Tiliroside was found to inhibit both monophenolase and diphenolase activity of mushroom tyrosinase. The lag time of tyrosine oxidation catalyzed by mushroom tyrosinase was obviously lengthened; 0.337 ...

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-b-D-glucopyranoside

[(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl-(2E)-3-(4-hydroxyphenyl)acrylat

Kaempferol-3-Glucoside-6''-p-coumaroyl

tiliroside

[(2R,3S,4S,5R,6S)-6-{[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl (2E)-3-(4-hydroxyphenyl)acrylate

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-β-D-glucopyranosyl]oxy]-

(2E)-3-(4-Hydroxyphényl)acrylate de [(2R,3S,4S,5R,6S)-6-{[5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-3-yl]oxy}-3,4,5-trihydroxytétrahydro-2H-pyran-2-yl]méthyle

trans-tiliroside

6-O-[(2E)-3-(4-Hydroxyphényl)-2-propènan-1-oyl]-β-D-glucopyranoside de 5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-3-yle

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside

6'-O-trans-p-CouMaroylastragalin

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]oxy]-

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl-6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside

BioBioPha
China
Product Name: tiliroside
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: tiliroside
Price: ￥6318.0/10mg ￥968.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Tiliroside
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: TILIROSIDE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Price: ￥312/5mg

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tiliroside

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