RM-581

• 常用名: RM-581
• 英文名: RM-581
• CAS号: 2086809-59-6
• 分子量: 646.82
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₀H₄₆N₄O₄
• 熔点: N/A
• 闪点: N/A

RM-581用途

RM-581是一种氨基甾体衍生物,对不同类型的癌症具有强大的抗癌活性,包括高死亡率胰腺癌[1]。

RM-581名称

• 英文名: RM-581

RM-581生物活性

• 描述: RM-581是一种氨基甾体衍生物,对不同类型的癌症具有强大的抗癌活性,包括高死亡率胰腺癌[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. René Maltais, et al. Minor chemical modifications of the aminosteroid derivative RM-581 lead to major impact on its anticancer activity, metabolic stability and aqueous solubility. Eur J Med Chem. 2020 Feb 15;188:111990.

RM-581物理化学性质

• 分子式: C₄₀H₄₆N₄O₄
• 分子量: 646.82
• InChIKey: ATNNMGSUEUFVSK-ZBFIBDPFSA-N
• SMILES: C#CC1(O)CCC2C3CCc4cc(OC)c(N5CCN(C(=O)C6CCCN6C(=O)c6ccc7ccccc7n6)CC5)cc4C3CCC21C

RM-581靶点实验

查看更多实验

实验名称：Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell ... 来源：ChEMBL 靶标：SK-OV-3 External Id：CHEMBL4683195

实验名称：Antiproliferative activity against human Caov-3 cells assessed as reduction in cell v... 来源：ChEMBL 靶标：Caov-3 cell line External Id：CHEMBL4683194

实验名称：Antiproliferative activity against human LAPC4 cells assessed as reduction in cell vi... 来源：ChEMBL 靶标：LAPC4 External Id：CHEMBL4683197

实验名称：Antiproliferative activity against human PC-3 cells assessed as reduction in cell via... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL4683196

实验名称：Antiproliferative activity against human MCF7 cells assessed as reduction in cell via... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4683199

实验名称：Antiproliferative activity against human LNCaP cells assessed as reduction in cell vi... 来源：ChEMBL 靶标：LNCaP External Id：CHEMBL4683198

实验名称：Antiproliferative activity against human OVCAR-3 cells assessed as reduction in cell ... 来源：ChEMBL 靶标：OVCAR-3 External Id：CHEMBL4683201

实验名称：Antiproliferative activity against human T47D cells assessed as reduction in cell via... 来源：ChEMBL 靶标：T47D External Id：CHEMBL4683200

实验名称：Antiproliferative activity against human LAPC4 cells assessed as reduction in cell vi... 来源：ChEMBL 靶标：LAPC4 External Id：CHEMBL4683187

实验名称：Antiproliferative activity against AR-deficient human PC3 cells assessed as reduction... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL4407245

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