HFY-4A

• 常用名: HFY-4A
• 英文名: HFY-4A
• CAS号: 2094810-82-7
• 分子量: 333.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₉N₃O₂
• 熔点: N/A
• 闪点: N/A

HFY-4A用途

HFY-4A 是一种 HDAC 抑制剂。HFY-4A 抑制乳腺癌细胞增殖、迁移和侵袭,并诱导细胞凋亡 (apoptosis)。HFY-4A 诱导免疫原性细胞死亡 (ICD)。HFY-4A 抑制乳腺癌异种移植小鼠模型中的肿瘤生长。

HFY-4A名称

• 英文名: HFY-4A

HFY-4A生物活性

• 描述: HFY-4A 是一种 HDAC 抑制剂。HFY-4A 抑制乳腺癌细胞增殖、迁移和侵袭,并诱导细胞凋亡 (apoptosis)。HFY-4A 诱导免疫原性细胞死亡 (ICD)。HFY-4A 抑制乳腺癌异种移植小鼠模型中的肿瘤生长。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> HDAC
  信号通路 >> 表观遗传学 >> HDAC
• 参考文献:

  [1]. Yin Y, et al. The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer. Toxicol Appl Pharmacol. 2023 Nov 1;478:116698.

HFY-4A物理化学性质

• 分子式: C₂₀H₁₉N₃O₂
• 分子量: 333.38
• 储存条件: -20℃

HFY-4A靶点实验

查看更多实验

实验名称：Induction of apoptosis in human K562 cells assessed as necrotic cells at 2 uM after 2... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033987

实验名称：Induction of apoptosis in human K562 cells assessed as late apoptotic cells at 2 uM a... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033988

实验名称：Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substr... 来源：ChEMBL 靶标：Histone deacetylase 2 External Id：CHEMBL4033995

实验名称：Induction of apoptosis in human K562 cells assessed as early apoptotic cells at 1 uM ... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033993

实验名称：Induction of apoptosis in human K562 cells assessed as viable cells at 1 uM after 24 ... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033994

实验名称：Induction of apoptosis in human K562 cells assessed as necrotic cells at 1 uM after 2... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033991

实验名称：Induction of apoptosis in human K562 cells assessed as late apoptotic cells at 1 uM a... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033992

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Induction of apoptosis in human K562 cells assessed as early apoptotic cells at 2 uM ... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033989

实验名称：Induction of apoptosis in human K562 cells assessed as viable cells at 2 uM after 24 ... 来源：ChEMBL 靶标：K562 External Id：CHEMBL4033990

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