TH1834

• 常用名: TH1834
• 英文名: TH1834
• CAS号: 2108830-08-4
• 分子量: 568.722
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₃H₄₀N₆O₃
• 熔点: N/A
• 闪点: N/A

TH1834用途

TH1834(TH-1834,TH 1834)是一种新型有效的特异性组蛋白乙酰转移酶Tip60抑制剂；诱导乳腺癌细胞系凋亡,细胞毒性高于星形孢菌素；增加癌细胞系PC-3和DU-145中的γH2AX病灶。结合IR；诱导细胞凋亡并增加乳腺癌细胞中未修复的DNA损伤。

TH1834名称

• 英文名: TH1834

TH1834生物活性

• 描述: TH1834(TH-1834,TH 1834)是一种新型有效的特异性组蛋白乙酰转移酶Tip60抑制剂；诱导乳腺癌细胞系凋亡,细胞毒性高于星形孢菌素；增加癌细胞系PC-3和DU-145中的γH2AX病灶。结合IR；诱导细胞凋亡并增加乳腺癌细胞中未修复的DNA损伤。
• 参考文献: References 1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372. View Related Products by Target Histone Acetyltransferase (HAT)

TH1834物理化学性质

• 分子式: C₃₃H₄₀N₆O₃
• 分子量: 568.722
• InChIKey: XERATECPNBWJFP-UHFFFAOYSA-N
• SMILES: O=C(O)Cn1nnc(-c2ccc(CN(CCCCOc3ccc(CN4CCCC4)cc3)CCc3ccccc3)cc2)n1

TH1834靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Inhibition of recombinant human GFP-tagged TIP60 expressed in chicken embryo DT40 cel... 来源：ChEMBL 靶标：Histone acetyltransferase KAT5 External Id：CHEMBL3779615

实验名称：Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyl... 来源：NCGC External Id：MTASE-f-cherrypicks

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

共23条，当前第1页，共3页

1

2

3