TH1834

Modify Date: 2024-02-28 16:55:19

TH1834 Structure
TH1834 structure
Common Name TH1834
CAS Number 2108830-08-4 Molecular Weight 568.722
Density N/A Boiling Point N/A
Molecular Formula C33H40N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TH1834


TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine; increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR; induces apoptosis and increases unrepaired DNA damage in breast cancer cells.

 Names

Name TH1834

 TH1834 Biological Activity

Description TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine; increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR; induces apoptosis and increases unrepaired DNA damage in breast cancer cells.
References References 1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372. View Related Products by Target Histone Acetyltransferase (HAT)

 Chemical & Physical Properties

Molecular Formula C33H40N6O3
Molecular Weight 568.722
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