地弗他酮

• 常用名: 地弗他酮
• 英文名: diftalone
• CAS号: 21626-89-1
• 分子量: 264.27900
• 密度: 1.43g/cm3
• 沸点: 462ºC at 760mmHg
• 分子式: C₁₆H₁₂N₂O₂
• 熔点: N/A
• 闪点: 221.2ºC

地弗他酮用途

Diftalone (Aladione) 是一种抗炎剂。Diftalone 可用于炎症性疾病的研究,例如类风湿性关节炎。

地弗他酮名称

• 中文名: 地弗他酮
• 英文名: 5,12-dihydrophthalazino[3,2-b]phthalazine-7,14-dione

地弗他酮生物活性

• 描述: Diftalone (Aladione) 是一种抗炎剂。Diftalone 可用于炎症性疾病的研究,例如类风湿性关节炎。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Della Porta G, et al. Carcinogenic activity in mice of diftalone, an anti-inflammatory agent. J Cancer Res Clin Oncol. 1984;108(3):308-11.

  [2]. Chalem F, et al. Diftalone: a new non-steroidal anti-inflammatory agent: comparative study with phenylbutazone in the treatment of rheumatoid arthritis. J Int Med Res. 1977;5(1):18-25.

地弗他酮物理化学性质

• 密度: 1.43g/cm3
• 沸点: 462ºC at 760mmHg
• 分子式: C₁₆H₁₂N₂O₂
• 分子量: 264.27900
• 闪点: 221.2ºC
• 精确质量: 264.09000
• PSA: 40.62000
• LogP: 2.08920
• InChIKey: CXSJGNHRBWJXEA-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2CN2C(=O)c3ccccc3CN12
• 蒸汽压: 1.03E-08mmHg at 25°C
• 折射率: 1.733

地弗他酮毒性和生态

地弗他酮安全信息

• 海关编码: 2933990090

地弗他酮海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

地弗他酮靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen 来源：NCGC External Id：tdp43-p2-repeat

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

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地弗他酮英文别名

• L 5418
• Aladione
• Diftalona [INN-Spanish]
• Phthalazino<2,3-b>phthalazin-5,12(7H,14H)-dion
• Diftalonum [INN-Latin]
• phthalazino<2,3-b>phthalazine-5,12-(14H,7H)dione
• DIFTALONE
• Phthalazino[2,3-b]phthalazine-5,12(7H,14H)-dione
• 7H,14H-phthalazino[2,3-b]phthalazine-5,12-dione
• Phthalazino<2,3-b>phthalazin-5(14H),12(7H)-dion
• EINECS 244-484-3
• phthalazino<2,3-b>phthalazine-5,12-dione