2-氯-4-(4-Boc-1-哌嗪基)嘧啶结构式
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常用名 | 2-氯-4-(4-Boc-1-哌嗪基)嘧啶 | 英文名 | tert-Butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate |
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| CAS号 | 221050-88-0 | 分子量 | 298.769 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 451.8±35.0 °C at 760 mmHg | |
| 分子式 | C13H19ClN4O2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 227.0±25.9 °C |
| 中文名 | 1-Boc-4-(2-氯嘧啶-4-基)哌嗪 |
|---|---|
| 英文名 | tert-butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate |
| 中文别名 | 2-氯-4-(4-BOC-1-哌嗪基)嘧啶 |
| 英文别名 | 更多 |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 451.8±35.0 °C at 760 mmHg |
| 分子式 | C13H19ClN4O2 |
| 分子量 | 298.769 |
| 闪点 | 227.0±25.9 °C |
| 精确质量 | 298.119659 |
| PSA | 58.56000 |
| LogP | 0.40 |
| InChIKey | GZYDEJABHMSOIM-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)N1CCN(c2ccnc(Cl)n2)CC1 |
| 蒸汽压 | 0.0±1.1 mmHg at 25°C |
| 折射率 | 1.550 |
| 储存条件 | 2-8°C |
| 危害码 (欧洲) | Xi |
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| 海关编码 | 2933990090 |
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~87%
2-氯-4-(4-Boc-1-... 221050-88-0 |
| 文献:Kono, Mitsunori; Matsumoto, Takahiro; Imaeda, Toshihiro; Kawamura, Toru; Fujimoto, Shinji; Kosugi, Yohei; Odani, Tomoyuki; Shimizu, Yuji; Matsui, Hideki; Shimojo, Masato; Kori, Masakuni Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1468 - 1478 |
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2-氯-4-(4-Boc-1-... 221050-88-0 |
| 文献:WO2011/95196 A1, ; Page/Page column 114 ; WO 2011/095196 A1 |
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2-氯-4-(4-Boc-1-... 221050-88-0 |
| 文献:US2005/176722 A1, ; Page/Page column 20; 22 ; |
| 2-氯-4-(4-Boc-1-哌嗪基)嘧啶上游产品 3 | |
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| 2-氯-4-(4-Boc-1-哌嗪基)嘧啶下游产品 0 | |
| 海关编码 | 2933990090 |
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| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:ULK1_INH_LUMI_1536_1X%INH PRUN
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mitogen-activated protein kinase kinase kinase 5 [Homo sapiens]
External Id:ASK1_INH_LUMI_1536_1X%INH
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实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
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| 1-Boc-4-(2-Chloropyrimidin-4-yl)piperazine |
| 1-Piperazinecarboxylic acid, 4-(2-chloro-4-pyrimidinyl)-, 1,1-dimethylethyl ester |
| tert-butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate |
| 2-Methyl-2-propanyl 4-(2-chloro-4-pyrimidinyl)-1-piperazinecarboxylate |