Atuzaginstat

• 常用名: Atuzaginstat
• 英文名: Atuzaginstat
• CAS号: 2211981-76-7
• 分子量: 386.41
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₅F₃N₂O₃
• 熔点: N/A
• 闪点: N/A

Atuzaginstat用途

Atuzaginstat(COR388)是一种有效的小分子细菌蛋白酶赖氨酸银杏蛋白酶抑制剂,可用于阿尔茨海默病的研究[1][2]。

Atuzaginstat名称

• 英文名: Atuzaginstat

Atuzaginstat生物活性

• 描述: Atuzaginstat(COR388)是一种有效的小分子细菌蛋白酶赖氨酸银杏蛋白酶抑制剂,可用于阿尔茨海默病的研究[1][2]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Lysine gingipain[1]

• 参考文献:

  [1]. Arastu-Kapur, S., et al. 676 PD-L1 is induced by the periodontal pathogen porphyromonas gingivalis and can be blocked by small molecule gingipain inhibitors, including atuzaginstat. Journal for Immuno Therapy of Cancer. 2020; 8(Suppl 3): A715-A715.

  [2]. Cortexyme Presents an Update and Baseline Data from the Phase 2/3 GAIN Trial of Atuzaginstat at CTAD 2020, the Clinical Trials on Alzheimer’s Disease Conference.

Atuzaginstat物理化学性质

• 分子式: C₁₉H₂₅F₃N₂O₃
• 分子量: 386.41

Atuzaginstat靶点实验

查看更多实验

实验名称：Inhibition Activity Assay from US Patent US11325884: "Ketone inhibitors of lysine gin... 来源：BindingDB 靶标：N/A External Id：BindingDB_10598_2

实验名称：Inhibition Assay from US Patent US11325884: "Ketone inhibitors of lysine gingipain" 来源：BindingDB 靶标：N/A External Id：BindingDB_10598_1

实验名称：Inhibition of Lysine Gingipain from US Patent US10730826: "Ketone inhibitors of lysin... 来源：BindingDB 靶标：N/A External Id：BindingDB_9257_1

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