P300/CBP-IN-3

• 常用名: P300/CBP-IN-3
• 英文名: P300/CBP-IN-3
• CAS号: 2299226-01-8
• 分子量: 431.53
• 密度: 1.23±0.1 g/cm3(Predicted)
• 沸点: N/A
• 分子式: C₂₄H₂₉N₇O
• 熔点: N/A
• 闪点: N/A

P300/CBP-IN-3用途

P300/CBP-IN-3, a p300/CBP 组蛋白乙酰转移酶 (histone acetyltransferase) 抑制剂,化合物 6,来源于专利 WO 2019049061 A1。

P300/CBP-IN-3名称

• 英文名: P300/CBP-IN-3

P300/CBP-IN-3生物活性

• 描述: P300/CBP-IN-3, a p300/CBP 组蛋白乙酰转移酶 (histone acetyltransferase) 抑制剂,化合物 6,来源于专利 WO 2019049061 A1。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 表观遗传学 >> 组蛋白乙酰转移酶
• 参考文献:

  [1]. Medina, et al. 5-(1H-Benzo[d]imidazol-2-yl)pyridin-2-amine and 5-(3H-imidazo[4,5-b]pyridin-6-yl)pyridin-2-amine derivatives as c-MYC and p300/CBP histone acetyltransferase inhibitors for treating cancer and their preparation.

P300/CBP-IN-3物理化学性质

• 密度: 1.23±0.1 g/cm3(Predicted)
• 分子式: C₂₄H₂₉N₇O
• 分子量: 431.53
• 储存条件: 2-8°C

P300/CBP-IN-3安全信息

• 危害码 (欧洲): Xi

P300/CBP-IN-3靶点实验

查看更多实验

实验名称：HAT Activity Inhibiting Assay from US Patent US20240122941: "THERAPY BASED ON SYNTHET... 来源：BindingDB 靶标：N/A External Id：BindingDB_11979_1

实验名称：Reduction in cMyc expression in human COLO 320HSR cells incubated for 24 hrs by HTRF ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5057214

实验名称：Decrease in nascent MYC mRNA level in human COLO 320HSR cells at 2 uM incubated for 7... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5057213

实验名称：Effect on MCL-1 protein level in human COLO 320HSR cells incubated for 24 hrs by West... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5057212

实验名称：Decrease in MYC mRNA level in human COLO 320HSR cells incubated for 6 hrs by qRT-PCR ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5057211

实验名称：Decrease in c-MYC protein level in human COLO 320HSR cells incubated for 24 hrs by We... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5057210

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