BPTF-IN-1

• 常用名: BPTF-IN-1
• 英文名: BPTF-IN-1
• CAS号: 2359618-49-6
• 分子量: 450.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃FN₆O₃
• 熔点: N/A
• 闪点: N/A

BPTF-IN-1用途

BPTF-IN-1(化合物AU1)是一种选择性溴代烷和含PHD指的转录因子(BPTF)溴代烷抑制剂,Kd为2.8μM。BPTF-IN-1对BPTF的选择性高于BRD4溴代烷。BPTF-IN-1显示出抗疟活性[1]。

BPTF-IN-1名称

• 英文名: BPTF-IN-1

BPTF-IN-1生物活性

• 描述: BPTF-IN-1(化合物AU1)是一种选择性溴代烷和含PHD指的转录因子(BPTF)溴代烷抑制剂,Kd为2.8μM。BPTF-IN-1对BPTF的选择性高于BRD4溴代烷。BPTF-IN-1显示出抗疟活性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 表观遗传学 >> 表观遗传读者域
• 参考文献:

  [1]. Steven E Kirberger, et al. Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor. Org Biomol Chem. 2019 Feb 13;17(7):2020-2027.

BPTF-IN-1物理化学性质

• 分子式: C₂₃H₂₃FN₆O₃
• 分子量: 450.47

BPTF-IN-1靶点实验

查看更多实验

实验名称：Upregulation of sfn mRNA in mouse EpH4 cells at 5 uM after 24 hrs by qRT-PCR analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4828248

实验名称：Upregulation of sprr1a mRNA in mouse EpH4 cells at 5 uM after 24 hrs by qRT-PCR analy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4828249

实验名称：Growth inhibition of mouse 4T1 cells BPTF knock down assessed as reduction cell viabi... 来源：ChEMBL 靶标：4T1 External Id：CHEMBL4828247

实验名称：Upregulation of Myc mRNA in mouse EpH4 cells at 5 uM after 24 hrs by qRT-PCR analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4828250

实验名称：NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L... 来源：DTP/NCI 靶标：N/A External Id：MCF7_OneDose

实验名称：NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell... 来源：DTP/NCI 靶标：N/A External Id：IGROV1_OneDose

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