Antitumor agent-F10

• 常用名: Antitumor agent-F10
• 英文名: Antitumor agent-F10
• CAS号: 2371727-65-8
• 分子量: 517.57
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₁N₃O₆
• 熔点: N/A
• 闪点: N/A

Antitumor agent-F10用途

抗肿瘤剂F10(化合物F10)是一种喜树碱衍生物。抗肿瘤药物F10是一种口服生物利用度高且有效的抗肿瘤药物。抗肿瘤药物F10的急性毒性低于SN-38,F10的溶解度达到9.86μg/mL【1】。

Antitumor agent-F10名称

• 英文名: Antitumor agent-F10

Antitumor agent-F10生物活性

• 描述: 抗肿瘤剂F10(化合物F10)是一种喜树碱衍生物。抗肿瘤药物F10是一种口服生物利用度高且有效的抗肿瘤药物。抗肿瘤药物F10的急性毒性低于SN-38,F10的溶解度达到9.86μg/mL【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Fan S, et al. F10, a new camptothecin derivative, was identified as a new orally-bioavailable, potent antitumor agent. Eur J Med Chem. 2020 Sep 15;202:112528.

Antitumor agent-F10物理化学性质

• 分子式: C₂₉H₃₁N₃O₆
• 分子量: 517.57

Antitumor agent-F10靶点实验

查看更多实验

实验名称：Induction of apoptosis in human HCT-116 cells assessed as early apoptotic cells level... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4708349

实验名称：Induction of apoptosis in human HCT-116 cells assessed as late apoptotic cells level ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4708348

实验名称：Induction of apoptosis in human HCT-116 cells assessed as early apoptotic cells level... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4708351

实验名称：Induction of apoptosis in human HCT-116 cells assessed as late apoptotic cells level ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4708350

实验名称：Solubility of compound in phosphate buffer at pH 7.4 incubated for 24 hrs under shaki... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708353

实验名称：Solubility of compound in phosphate buffer at pH 4.5 incubated for 24 hrs under shaki... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708352

实验名称：Antitumor activity against human HCT-116 cells xenografted in nude BALB/c mouse asses... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4708355

实验名称：Solubility of compound in water incubated for 24 hrs under shaking condition by HPLC ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708354

实验名称：Inhibition of human recombinant topoisomerase I using DNA pBR322 as substrate assesse... 来源：ChEMBL 靶标：DNA topoisomerase 1 External Id：CHEMBL4708341

实验名称：Inhibition of human recombinant topoisomerase I using DNA pBR322 as substrate assesse... 来源：ChEMBL 靶标：DNA topoisomerase 1 External Id：CHEMBL4708343

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