离子交换树脂

• 常用名: 离子交换树脂
• 英文名: thiamphenicol
• CAS号: 2393-92-2
• 分子量: 413.27400
• 密度: 1.468g/cm3
• 沸点: 672.5ºC at 760mmHg
• 分子式: C₁₄H₁₈Cl₂N₂O₆S
• 熔点: 163-166ºC
• 闪点: 360.5ºC

离子交换树脂用途

甘氨酸Thiamphenicol,一种α-氨基酸酯,是Thiampheniol(HY-B0479)的前药[1]。

离子交换树脂名称

• 中文名: 离子交换树脂
• 英文名: [(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-methylsulfonylphenyl)propyl] 2-aminoacetate

离子交换树脂生物活性

• 描述: 甘氨酸Thiamphenicol,一种α-氨基酸酯,是Thiampheniol(HY-B0479)的前药[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Chen X, et al. Simultaneous analysis of thiamphenicol and its prodrug thiamphenicol glycinate in human plasma and urine by high performance liquid chromatography: application to pharmacokinetic study. J Pharm Biomed Anal. 2006 Jun 7;41(3):943-9.

离子交换树脂物理化学性质

• 密度: 1.468g/cm3
• 沸点: 672.5ºC at 760mmHg
• 熔点: 163-166ºC
• 分子式: C₁₄H₁₈Cl₂N₂O₆S
• 分子量: 413.27400
• 闪点: 360.5ºC
• 精确质量: 412.02600
• PSA: 144.17000
• LogP: 2.08590
• InChIKey: AMGKHLVPQHMHGQ-ZYHUDNBSSA-N
• SMILES: CS(=O)(=O)c1ccc(C(O)C(COC(=O)CN)NC(=O)C(Cl)Cl)cc1
• 储存条件: 0-6°C
• 水溶解性: ethanol: 50 mg/mL, clear, colorless

离子交换树脂安全信息

• 安全声明 (欧洲): 22-24/25
• WGK德国: 2
• RTECS号: AB6680000

离子交换树脂靶点实验

查看更多实验

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：ULK1_INH_LUMI_1536_1X%INH PRUN

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：S16 Schwann cell PMP22 intronic element firefly luciferase assay 来源：NCGC 靶标：peripheral myelin protein 22 [Rattus norvegicus] External Id：cmt-p4-fluc-fda_regid

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

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离子交换树脂英文别名

• Thiamphenicol glycinate
• (2r,3r)-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate
• HMS2090E09