Anticancer agent 25

更新时间：2025-08-26 13:46:14

Anticancer agent 25用途

抗癌剂25对PC3细胞具有最强的细胞毒性,IC50值为0.19μM。

英文名	Anticancer agent 25

描述	抗癌剂25对PC3细胞具有最强的细胞毒性,IC50值为0.19μM。
相关类别	研究领域 >> 癌症信号通路 >> 其他 >> 其他
靶点实验	Cell Cycle/DNA Damage:0.19 μM (IC50)
参考文献	[1]. Wang ZC, et al. Synthesis and anticancer activity of novel 9,13-disubstituted berberine derivatives. Bioorg Med Chem Lett. 2020 Jan 15;30(2):126821.

分子式	C₃₇H₄₅BrN₂O₃
分子量	645.67
InChIKey	CWISSTVNSNYSFG-UHFFFAOYSA-N
SMILES	CCCCCCCCNc1c(OC)ccc2c(Cc3ccc(C(C)C)cc3)c3[n+](cc12)CCc1cc2c(cc1-3)OCO2.[Br-]

实验名称：Induction of cell cycle arrest in human PC3 cells assessed as accumulation at G1 phas...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603723

实验名称：Induction of cell cycle arrest in human PC3 cells assessed as accumulation at G1 phas...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603722

实验名称：Induction of cell cycle arrest in human PC3 cells assessed as accumulation at G1 phas...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603725

实验名称：Induction of cell cycle arrest in human PC3 cells assessed as accumulation at G1 phas...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603724

实验名称：Inhibition of colony formation in human PC3 cells at 0.1 uM measured after 1 week by ...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603727

实验名称：Induction of cell cycle arrest in human PC3 cells assessed as reduction in cell popul...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603726

实验名称：Inhibition of colony formation in human PC3 cells at 1 uM measured after 1 week by cr...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603729

实验名称：Inhibition of colony formation in human PC3 cells at 0.5 uM measured after 1 week by ...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603728

实验名称：Antiproliferative activity against human PC3 cells assessed as cell growth inhibition...
来源：ChEMBL
靶标：PC-3
External Id：CHEMBL4603715

实验名称：Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inh...
来源：ChEMBL
靶标：MDA-MB-231
External Id：CHEMBL4603717

共21条，当前第1页，共3页