Chitin synthase inhibitor 3

• 常用名: Chitin synthase inhibitor 3
• 英文名: Chitin synthase inhibitor 3
• CAS号: 2416338-26-4
• 分子量: 365.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₉N₃O₄
• 熔点: N/A
• 闪点: N/A

Chitin synthase inhibitor 3用途

几丁质合成酶抑制剂3(化合物2d)是一种有效的几丁质合酶抑制剂,IC50值为0.16 mM,对白色念珠菌的MIC为1µg/mL。抗真菌活性[1]。

Chitin synthase inhibitor 3名称

• 英文名: Chitin synthase inhibitor 3

Chitin synthase inhibitor 3生物活性

• 描述: 几丁质合成酶抑制剂3(化合物2d)是一种有效的几丁质合酶抑制剂,IC50值为0.16 mM,对白色念珠菌的MIC为1µg/mL。抗真菌活性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 靶点实验:

  IC50: 0.16 mM (chitin synthase)[1] MIC: 1 µg/mL in candida albicans[1]

• 参考文献:

  [1]. Li B, et al. Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1H)-quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2020 Jun 1;195:112278.

Chitin synthase inhibitor 3物理化学性质

• 分子式: C₂₀H₁₉N₃O₄
• 分子量: 365.38

Chitin synthase inhibitor 3靶点实验

查看更多实验

实验名称：Antibacterial activity against Campylobacter coli JM 109 来源：ChEMBL 靶标：Campylobacter coli External Id：CHEMBL4768930

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4768931

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 25923 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4768928

实验名称：Antibacterial activity against Bacillus subtilis ATCC 6633 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL4768929

实验名称：Antibacterial activity against Bacillus proteus ATCC 8427 来源：ChEMBL 靶标：Proteus vulgaris External Id：CHEMBL4768932

实验名称：Antifungal activity against Candida albicans ATCC 90023 incubated for 48 hrs by two-f... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4768922

实验名称：Antifungal activity against Cryptococcus neoformans ATCC 32719 incubated for 48 hrs b... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL4768923

实验名称：Inhibition of Candida tropicalis ATCC 750 chitin synthase using UDP-GlcNAc as substra... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768920

实验名称：Antifungal activity against Candida albicans ATCC 76615 incubated for 48 hrs by two-f... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4768926

实验名称：Antifungal activity against Aspergillus fumigatus GIMCC 3.19 incubated for 48 hrs by ... 来源：ChEMBL 靶标：Aspergillus fumigatus External Id：CHEMBL4768927

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