Haspin-IN-3

• 常用名: Haspin-IN-3
• 英文名: Haspin-IN-3
• CAS号: 2416569-95-2
• 分子量: 278.26
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₀N₂O₃
• 熔点: N/A
• 闪点: N/A

Haspin-IN-3用途

Haspin-IN-3(化合物8l)是一种有效的Haspin抑制剂,IC50为14 nM。Haspin-IN-3具有抗癌作用[1]。

Haspin-IN-3名称

• 英文名: Haspin-IN-3

Haspin-IN-3生物活性

• 描述: Haspin-IN-3(化合物8l)是一种有效的Haspin抑制剂,IC50为14 nM。Haspin-IN-3具有抗癌作用[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> Haspin激酶
• 靶点实验:

  IC50: 14 nM (Haspin)[1]

• 参考文献:

  [1]. Malikotsi A Qhobosheane, et al. Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors. Bioorg Med Chem. 2020 Jun 1;28(11):115468.

Haspin-IN-3物理化学性质

• 分子式: C₁₆H₁₀N₂O₃
• 分子量: 278.26
• InChIKey: VHCZWXXMSGKCKC-NSIKDUERSA-N
• SMILES: O=C1C(=Cc2c[nH]c3ncccc23)Oc2cc(O)ccc21

Haspin-IN-3靶点实验

查看更多实验

实验名称：Inhibition of human CDK2/Cyclin A assessed as residual activity at 1 uM using Histone... 来源：ChEMBL 靶标：Cyclin-A2 External Id：CHEMBL4620599

实验名称：Inhibition of human recombinant CDK9/Cyclin T expressed in baculovirus in Sf9 insect ... 来源：ChEMBL 靶标：Cyclin-dependent kinase 9 External Id：CHEMBL4620601

实验名称：Inhibition of human recombinant CDK5/p25 expressed in bacteria assessed as residual a... 来源：ChEMBL 靶标：Cyclin-dependent kinase 5 External Id：CHEMBL4620600

实验名称：Inhibition of human recombinant PIM1 expressed in bacteria assessed as residual activ... 来源：ChEMBL 靶标：Serine/threonine-protein kinase pim-1 External Id：CHEMBL4620603

实验名称：Inhibition of human recombinant Haspin (470 to 798 residues) expressed in bacteria as... 来源：ChEMBL 靶标：Serine/threonine-protein kinase haspin External Id：CHEMBL4620602

实验名称：Inhibition of porcine GSK3-alpha/GSK3-Beta assessed as residual activity at 1 uM usin... 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL4620605

实验名称：Inhibition of porcine CK1-delta assessed as residual activity at 1 uM using RRKHAAIGS... 来源：ChEMBL 靶标：Casein kinase 1, delta tv1 External Id：CHEMBL4620604

实验名称：Inhibition of leishmania major CK1 at 1 uM using RRKHAAIGSpAYSIT as substrate in pres... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4620607

实验名称：Inhibition of human recombinant CDK9/Cyclin T expressed in baculovirus in Sf9 insect ... 来源：ChEMBL 靶标：Cyclin-dependent kinase 9 External Id：CHEMBL4620609

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